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<StructureSection load='6jtb' size='340' side='right'caption='[[6jtb]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
<StructureSection load='6jtb' size='340' side='right'caption='[[6jtb]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6jtb]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JTB OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6JTB FirstGlance]. <br>
<table><tr><td colspan='2'>[[6jtb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Porphyromonas_gingivalis_ATCC_33277 Porphyromonas gingivalis ATCC 33277]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6JTB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6JTB FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4y04|4y04]]</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CIT:CITRIC+ACID'>CIT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6jtb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jtb OCA], [http://pdbe.org/6jtb PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6jtb RCSB], [http://www.ebi.ac.uk/pdbsum/6jtb PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6jtb ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6jtb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6jtb OCA], [https://pdbe.org/6jtb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6jtb RCSB], [https://www.ebi.ac.uk/pdbsum/6jtb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6jtb ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/DPP11_PORG3 DPP11_PORG3]] Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Shows a strict specificity for acidic residues (Asp or Glu) in the P1 position, and has a hydrophobic residue preference at the P2 position. Preferentially cleaves the synthetic substrate Leu-Asp-methylcoumaryl-7-amide (Leu-Asp-MCA) as compared to Leu-Glu-MCA. Is involved in amino acid metabolism and bacterial growth of asaccharolytic P.gingivalis, that utilizes amino acids from extracellular proteinaceous nutrients as energy and carbon sources.<ref>PMID:21896480</ref> <ref>PMID:23246913</ref>
[https://www.uniprot.org/uniprot/DPP11_PORG3 DPP11_PORG3] Catalyzes the removal of dipeptides from the N-terminus of oligopeptides. Shows a strict specificity for acidic residues (Asp or Glu) in the P1 position, and has a hydrophobic residue preference at the P2 position. Preferentially cleaves the synthetic substrate Leu-Asp-methylcoumaryl-7-amide (Leu-Asp-MCA) as compared to Leu-Glu-MCA. Is involved in amino acid metabolism and bacterial growth of asaccharolytic P.gingivalis, that utilizes amino acids from extracellular proteinaceous nutrients as energy and carbon sources.<ref>PMID:21896480</ref> <ref>PMID:23246913</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6jtb" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6jtb" style="background-color:#fffaf0;"></div>
==See Also==
*[[Dipeptidyl peptidase 3D structures|Dipeptidyl peptidase 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Iizuka, I]]
[[Category: Porphyromonas gingivalis ATCC 33277]]
[[Category: Kushibiki, C]]
[[Category: Iizuka I]]
[[Category: Nakamura, A]]
[[Category: Kushibiki C]]
[[Category: Ogasawara, W]]
[[Category: Nakamura A]]
[[Category: Roppongi, S]]
[[Category: Ogasawara W]]
[[Category: Sakamoto, Y]]
[[Category: Roppongi S]]
[[Category: Suzuki, Y]]
[[Category: Sakamoto Y]]
[[Category: Tanaka, N]]
[[Category: Suzuki Y]]
[[Category: Antimicrobial]]
[[Category: Tanaka N]]
[[Category: Dipeptidyl aminopeptidase]]
[[Category: Hydrolase]]
[[Category: Microgravity]]
[[Category: Perio]]
[[Category: S46]]
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