RNA Polymerase II: Difference between revisions
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== Structural Components == | == Structural Components == | ||
Like in much of biochemistry, the structure of RNAP II gives insights into its function. | |||
This is an image with all of the following discussed structures within one image. | |||
The <scene name='82/824648/Clamp/2'>clamp</scene> swings to trap the DNA in the cleft. Further along, the <scene name='82/824648/Wall/1'>wall</scene> sends the DNA template through the cleft in approximately a 90° turn. Both the clamp and wall are parts of the Rpb2 subunit. Further along in the process, the <scene name='82/824648/Rudder/1'>rudder</scene> separates the newly synthesized RNA strand from the DNA template. The DNA reforms into a double helix as it leaves RNA pol II. | The <scene name='82/824648/Clamp/2'>clamp</scene> swings to trap the DNA in the cleft. Further along, the <scene name='82/824648/Wall/1'>wall</scene> sends the DNA template through the cleft in approximately a 90° turn. Both the clamp and wall are parts of the Rpb2 subunit. Further along in the process, the <scene name='82/824648/Rudder/1'>rudder</scene> separates the newly synthesized RNA strand from the DNA template. The DNA reforms into a double helix as it leaves RNA pol II. | ||
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== Notes == | == Notes == | ||
From structural components: | From structural components: | ||
Structural overview: [PDB: 5VVR: with highlighted sections mentioned below] | |||
Bridge: Depicted: [PDB: 1I6H: 810-845.a] | Bridge: Depicted: [PDB: 1I6H: 810-845.a] | ||
