6puj: Difference between revisions

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~~'''Unreleased structure'''~~

~~The entry~~ 6puj is ~~ON HOLD~~ ~~until Paper Publication~~

==Structure of human MAIT A-F7 TCR in complex with human MR1-3`OH-Propyl-5-OP-U==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6puj]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PUJ FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=Q7S:6-[(3-hydroxypropyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione'>Q7S</scene></td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6puj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6puj OCA], [http://pdbe.org/6puj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6puj RCSB], [http://www.ebi.ac.uk/pdbsum/6puj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6puj ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/HMR1_HUMAN HMR1_HUMAN]] Has antigen presentation function. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT cells are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.<ref>PMID:12794138</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Awad, W]]

[[Category: Keller, A N]]

[[Category: Rossjohn, J]]

[[Category: Immune system]]

[[Category: Mait]]

[[Category: Metablite presentation]]

[[Category: Mr1]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6puj is ON HOLD  until Paper Publication
+==Structure of human MAIT A-F7 TCR in complex with human MR1-3`OH-Propyl-5-OP-U==
+<StructureSection load='6puj' size='340' side='right'caption='[[6puj]], [[Resolution|resolution]] 1.92&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6puj]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PUJ FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=Q7S:6-[(3-hydroxypropyl)amino]-5-[(E)-(2-oxopropylidene)amino]pyrimidine-2,4(1H,3H)-dione'>Q7S</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6puj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6puj OCA], [http://pdbe.org/6puj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6puj RCSB], [http://www.ebi.ac.uk/pdbsum/6puj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6puj ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/HMR1_HUMAN HMR1_HUMAN]] Has antigen presentation function. Involved in the development and expansion of a small population of T-cells expressing an invariant T-cell receptor alpha chain called mucosal-associated invariant T-cells (MAIT). MAIT cells are preferentially located in the gut lamina propria and therefore may be involved in monitoring commensal flora or serve as a distress signal. Expression and MAIT cell recognition seem to be ligand-dependent.<ref>PMID:12794138</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Awad, W]]
+[[Category: Keller, A N]]
+[[Category: Rossjohn, J]]
+[[Category: Immune system]]
+[[Category: Mait]]
+[[Category: Metablite presentation]]
+[[Category: Mr1]]