1c4e: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[1c4e]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Gymnema_sylvestre Gymnema sylvestre]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2gur 2gur]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C4E OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1C4E FirstGlance]. <br>

<table><tr><td colspan='2'>[[1c4e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gymnema_sylvestre Gymnema sylvestre]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2gur 2gur]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C4E FirstGlance]. <br>

</td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gur|2gur]]</td></tr>

<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2gur|2gur]]</div></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=1c4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c4e OCA], [~~http~~://pdbe.org/1c4e PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=1c4e RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/1c4e PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=1c4e ProSAT]</span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c4e OCA], [https://pdbe.org/1c4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c4e RCSB], [https://www.ebi.ac.uk/pdbsum/1c4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c4e ProSAT]</span></td></tr>

</table>

== Function ==

[[~~http~~://www.uniprot.org/uniprot/GUR_GYMSY GUR_GYMSY]] Suppresses strongly the sweet taste responses in the rat with high specificity to sucrose, glucose, glycine, and saccharin. This effect is reversible, but complete recovery of the suppressed responses required at least 3h. Gurmarin showed no effect or only a very weak effect on the sweet taste sensation in humans.

[[https://www.uniprot.org/uniprot/GUR_GYMSY GUR_GYMSY]] Suppresses strongly the sweet taste responses in the rat with high specificity to sucrose, glucose, glycine, and saccharin. This effect is reversible, but complete recovery of the suppressed responses required at least 3h. Gurmarin showed no effect or only a very weak effect on the sweet taste sensation in humans.

== Publication Abstract from PubMed ==

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 <StructureSection load='1c4e' size='340' side='right'caption='[[1c4e]], [[NMR_Ensembles_of_Models | 20 NMR models]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[1c4e]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gymnema_sylvestre Gymnema sylvestre]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2gur 2gur]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C4E OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1C4E FirstGlance]. <br>
+<table><tr><td colspan='2'>[[1c4e]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gymnema_sylvestre Gymnema sylvestre]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2gur 2gur]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1C4E OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1C4E FirstGlance]. <br>
 </td></tr><tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
-<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2gur|2gur]]</td></tr>
+<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2gur|2gur]]</div></td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1c4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c4e OCA], [http://pdbe.org/1c4e PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1c4e RCSB], [http://www.ebi.ac.uk/pdbsum/1c4e PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1c4e ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1c4e FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1c4e OCA], [https://pdbe.org/1c4e PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1c4e RCSB], [https://www.ebi.ac.uk/pdbsum/1c4e PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1c4e ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/GUR_GYMSY GUR_GYMSY]] Suppresses strongly the sweet taste responses in the rat with high specificity to sucrose, glucose, glycine, and saccharin. This effect is reversible, but complete recovery of the suppressed responses required at least 3h. Gurmarin showed no effect or only a very weak effect on the sweet taste sensation in humans.
+[[https://www.uniprot.org/uniprot/GUR_GYMSY GUR_GYMSY]] Suppresses strongly the sweet taste responses in the rat with high specificity to sucrose, glucose, glycine, and saccharin. This effect is reversible, but complete recovery of the suppressed responses required at least 3h. Gurmarin showed no effect or only a very weak effect on the sweet taste sensation in humans.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==