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<StructureSection load='6rpu' size='340' side='right'caption='[[6rpu]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
<StructureSection load='6rpu' size='340' side='right'caption='[[6rpu]], [[Resolution|resolution]] 2.11&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6rpu]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Ashgo Ashgo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RPU OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6RPU FirstGlance]. <br>
<table><tr><td colspan='2'>[[6rpu]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Eremothecium_gossypii_ATCC_10895 Eremothecium gossypii ATCC 10895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6RPU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6RPU FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=G5P:P1-(5-ADENOSYL)-P5-(5-GUANOSYL)+PENTAPHOSPHATE'>G5P</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.11&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AGOS_AER117W ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=284811 ASHGO])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=G5P:P1-(5-ADENOSYL)-P5-(5-GUANOSYL)+PENTAPHOSPHATE'>G5P</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/IMP_dehydrogenase IMP dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.205 1.1.1.205] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6rpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rpu OCA], [https://pdbe.org/6rpu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6rpu RCSB], [https://www.ebi.ac.uk/pdbsum/6rpu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6rpu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6rpu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6rpu OCA], [http://pdbe.org/6rpu PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6rpu RCSB], [http://www.ebi.ac.uk/pdbsum/6rpu PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6rpu ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/Q756Z6_ASHGO Q756Z6_ASHGO]] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_03156]  
[https://www.uniprot.org/uniprot/Q756Z6_ASHGO Q756Z6_ASHGO] Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.[HAMAP-Rule:MF_03156]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Ashgo]]
[[Category: Eremothecium gossypii ATCC 10895]]
[[Category: IMP dehydrogenase]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Buey, R M]]
[[Category: Buey RM]]
[[Category: Fernandez-Justel, D]]
[[Category: Fernandez-Justel D]]
[[Category: Revuelta, J L]]
[[Category: Revuelta JL]]
[[Category: Bateman domain]]
[[Category: Dinucleoside polyphosphate]]
[[Category: Imp dehydrogenase]]
[[Category: Oxidoreductase]]
Retrieved from "https://proteopedia.org/6rpu"