3b92: Difference between revisions

@@ Line 1: / Line 1: @@
-[[Image:3b92.jpg|left|200px]]
+{{Seed}}
+[[Image:3b92.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_3b92|  PDB=3b92  |  SCENE=  }}
-'''Novel thio-based TACE inhibitors Part 2: Rational design, synthesis and SAR of thiol-contaning aryl sufones'''
+===Novel thio-based TACE inhibitors Part 2: Rational design, synthesis and SAR of thiol-contaning aryl sufones===
-==Overview==
+<!--
-A series of potent thiol-containing aryl sulfone TACE inhibitors were designed and synthesized. The SAR and MMP selectivity of the series were investigated. In particular, compound 8b showed excellent in vitro potency against the isolated enzyme and good selectivity over MMP-2, -7, -8, -9, and -13. The X-ray structure of 8b in complex with TACE was also obtained.
+The line below this paragraph, {{ABSTRACT_PUBMED_18054488}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 18054488 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_18054488}}
 ==About this Structure==
@@ Line 41: / Line 45: @@
 [[Category: Zinc]]
 [[Category: Zymogen]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed Apr 30 13:36:51 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 11:24:52 2008''

Navigation menu