Virion infectivity factor

spinqualitylabelsall models HIV-1 virion infectivity factor (deep sky blue) complex with human elongin-B (green) and elongin-C (pink) (PDB code 2ma9) Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Function Virion infectivity factor (Vif) of HIV-1 is essential for efficient viral replication by binding to the a component of the innate immune system and triggering its polyubiquitination and rapid degradation thus preventing its entry into progeny virions. Interactions between HIV-1 virion infectivity factor and human elongin-B and elongin-C. For details see HIV and accessory proteins

3D Structures of virion infectivity factor

Updated on 25-March-2020

HIV and accessory proteins – Vif + cullin-5 + elongin-C + elongin-B + CBF-β – HIV-1
2ma9, 3dcg – Vif + elongin-C + elongin-B – HIV-1
6nil – Vif + CBF-β + AF3 – HIV-1 - Cry EM
6p59 – Vif + elongin-C + elongin-B + CBF-β – SIV-1

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