4v2r: Difference between revisions
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<StructureSection load='4v2r' size='340' side='right'caption='[[4v2r]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='4v2r' size='340' side='right'caption='[[4v2r]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[4v2r]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[4v2r]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Taxus_chinensis Taxus chinensis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4V2R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4V2R FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MDO:{2-[(1S)-1-AMINOETHYL]-4-METHYLIDENE-5-OXO-4,5-DIHYDRO-1H-IMIDAZOL-1-YL}ACETIC+ACID'>MDO</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4v2r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4v2r OCA], [https://pdbe.org/4v2r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4v2r RCSB], [https://www.ebi.ac.uk/pdbsum/4v2r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4v2r ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/PAM_TAXWC PAM_TAXWC] Phenylalanine aminomutase that catalyzes the rearrangement of L-phenylalanine to R-beta-phenylalanine. Catalyzes the first commited step in the biosynthesis of the side chain of the alkaloid taxol (paclitaxel), a widely-used compound with antitumor activity. Has also low phenylalanine ammonia-lyase activity and can catalyze the amination of trans-cinnamate.<ref>PMID:15878763</ref> <ref>PMID:22113970</ref> <ref>PMID:24786474</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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==See Also== | ==See Also== | ||
*[[Aminomutase 3D structures|Aminomutase 3D structures]] | *[[Aminomutase 3D structures|Aminomutase 3D structures]] | ||
*[[Ubiquitin protein ligase|Ubiquitin protein ligase]] | *[[Ubiquitin protein ligase 3D structures|Ubiquitin protein ligase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: Bartsch | [[Category: Taxus chinensis]] | ||
[[Category: Dijkstra | [[Category: Bartsch S]] | ||
[[Category: Heberling | [[Category: Dijkstra BW]] | ||
[[Category: Janssen | [[Category: Heberling M]] | ||
[[Category: Marrink | [[Category: Janssen D]] | ||
[[Category: Masman | [[Category: Marrink S]] | ||
[[Category: Wybenga | [[Category: Masman M]] | ||
[[Category: Wybenga GG]] | |||