1fx7: Difference between revisions

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<StructureSection load='1fx7' size='340' side='right'caption='[[1fx7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='1fx7' size='340' side='right'caption='[[1fx7]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[1fx7]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FX7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1FX7 FirstGlance]. <br>
<table><tr><td colspan='2'>[[1fx7]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_tuberculosis"_(zopf_1883)_klein_1884 "bacillus tuberculosis" (zopf 1883) klein 1884]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1FX7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1FX7 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1b1b|1b1b]], [[1bi0|1bi0]], [[1bi1|1bi1]], [[1bi2|1bi2]], [[1bi3|1bi3]], [[1bym|1bym]], [[1c0w|1c0w]], [[1ddn|1ddn]], [[1dpr|1dpr]], [[2dtr|2dtr]], [[2tdx|2tdx]]</td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1b1b|1b1b]], [[1bi0|1bi0]], [[1bi1|1bi1]], [[1bi2|1bi2]], [[1bi3|1bi3]], [[1bym|1bym]], [[1c0w|1c0w]], [[1ddn|1ddn]], [[1dpr|1dpr]], [[2dtr|2dtr]], [[2tdx|2tdx]]</div></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1fx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fx7 OCA], [http://pdbe.org/1fx7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1fx7 RCSB], [http://www.ebi.ac.uk/pdbsum/1fx7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1fx7 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1fx7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1fx7 OCA], [https://pdbe.org/1fx7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1fx7 RCSB], [https://www.ebi.ac.uk/pdbsum/1fx7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1fx7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/IDER_MYCTU IDER_MYCTU]] Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism. Acts as a repressor of siderophore biosynthesis and as a positive modulator of iron storage. Also regulates expression of transporters, proteins involved in siderophore synthesis, iron storage and transcriptional regulators.<ref>PMID:11722747</ref> <ref>PMID:12065475</ref>   
[[https://www.uniprot.org/uniprot/IDER_MYCTU IDER_MYCTU]] Metal-dependent DNA-binding protein that controls transcription of many genes involved in iron metabolism. Acts as a repressor of siderophore biosynthesis and as a positive modulator of iron storage. Also regulates expression of transporters, proteins involved in siderophore synthesis, iron storage and transcriptional regulators.<ref>PMID:11722747</ref> <ref>PMID:12065475</ref>   
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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