6uuj: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6uuj is ~~ON HOLD~~ ~~until Paper Publication~~

==Structure of PE5-PPE4-EspG3 complex from the type VII (ESX-3) secretion system, space group P212121==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6uuj]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UUJ FirstGlance]. <br>

~~Description~~:

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6vhr|6vhr]]</td></tr>

[[Category: ~~Unreleased Structures~~]]

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uuj OCA], [http://pdbe.org/6uuj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uuj RCSB], [http://www.ebi.ac.uk/pdbsum/6uuj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uuj ProSAT]</span></td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/PE05_MYCTU PE05_MYCTU]] Important for the siderophore-mediated iron-acquisition function of ESX-3 (PubMed:26729876). May play a pivotal role in the evasion of host immune response by M.tuberculosis. Mediates production of IL-10 via activation of the p38 and ERK1/2 mitogen-activated protein kinase (MAPK) signaling pathways (PubMed:23284742).<ref>PMID:23284742</ref> <ref>PMID:26729876</ref> [[http://www.uniprot.org/uniprot/PPE04_MYCTU PPE04_MYCTU]] Important for the siderophore-mediated iron-acquisition function of ESX-3.<ref>PMID:26729876</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Korotkov, K V]]

[[Category: Williamson, Z A]]

[[Category: Chaperone]]

[[Category: Protein secretion]]

[[Category: Protein transport]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6uuj is ON HOLD  until Paper Publication
+==Structure of PE5-PPE4-EspG3 complex from the type VII (ESX-3) secretion system, space group P212121==
+<StructureSection load='6uuj' size='340' side='right'caption='[[6uuj]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6uuj]] is a 12 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UUJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UUJ FirstGlance]. <br>
-Description:
+</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[6vhr|6vhr]]</td></tr>
-[[Category: Unreleased Structures]]
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uuj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uuj OCA], [http://pdbe.org/6uuj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uuj RCSB], [http://www.ebi.ac.uk/pdbsum/6uuj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uuj ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/PE05_MYCTU PE05_MYCTU]] Important for the siderophore-mediated iron-acquisition function of ESX-3 (PubMed:26729876). May play a pivotal role in the evasion of host immune response by M.tuberculosis. Mediates production of IL-10 via activation of the p38 and ERK1/2 mitogen-activated protein kinase (MAPK) signaling pathways (PubMed:23284742).<ref>PMID:23284742</ref> <ref>PMID:26729876</ref>  [[http://www.uniprot.org/uniprot/PPE04_MYCTU PPE04_MYCTU]] Important for the siderophore-mediated iron-acquisition function of ESX-3.<ref>PMID:26729876</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Korotkov, K V]]
+[[Category: Williamson, Z A]]
+[[Category: Chaperone]]
+[[Category: Protein secretion]]
+[[Category: Protein transport]]