5hu3: Difference between revisions

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<StructureSection load='5hu3' size='340' side='right'caption='[[5hu3]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
<StructureSection load='5hu3' size='340' side='right'caption='[[5hu3]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5hu3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Drome Drome]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HU3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HU3 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5hu3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HU3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HU3 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.885&#8491;</td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=TPO:PHOSPHOTHREONINE'>TPO</scene></td></tr>
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fg8|5fg8]], [[5h9b|5h9b]]</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hu3 OCA], [https://pdbe.org/5hu3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hu3 RCSB], [https://www.ebi.ac.uk/pdbsum/5hu3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hu3 ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CaMKII, CaM, CG18069 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME]), eag, CG10952 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7227 DROME])</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Calcium/calmodulin-dependent_protein_kinase Calcium/calmodulin-dependent protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.17 2.7.11.17] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hu3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hu3 OCA], [http://pdbe.org/5hu3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hu3 RCSB], [http://www.ebi.ac.uk/pdbsum/5hu3 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5hu3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/KCC2A_DROME KCC2A_DROME]] A key regulator of plasticity in synaptic physiology and behavior, alterations in its activity produce pleiotrophic effects that involve synaptic transmission and development as well as various aspects of behavior. Directly modulates eag potassium channels.<ref>PMID:11980904</ref> <ref>PMID:14687552</ref> [[http://www.uniprot.org/uniprot/KCNAE_DROME KCNAE_DROME]] Structural component of a potassium channel. Mediates the potassium permeability of membranes; potassium current is regulated by CaMKII and CASK. Has a role in growth of the perineurial glial layer of the larval peripheral nerve.<ref>PMID:11517334</ref> <ref>PMID:11980904</ref> <ref>PMID:15901771</ref> <ref>PMID:1840699</ref> 
[https://www.uniprot.org/uniprot/KCC2A_DROME KCC2A_DROME] A key regulator of plasticity in synaptic physiology and behavior, alterations in its activity produce pleiotrophic effects that involve synaptic transmission and development as well as various aspects of behavior. Directly modulates eag potassium channels.<ref>PMID:11980904</ref> <ref>PMID:14687552</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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==See Also==
==See Also==
*[[Calcium/calmodulin dependent protein kinase 3D structures|Calcium/calmodulin dependent protein kinase 3D structures]]
*[[Calcium/calmodulin dependent protein kinase 3D structures|Calcium/calmodulin dependent protein kinase 3D structures]]
*[[Potassium Channel|Potassium Channel]]
*[[Potassium channel 3D structures|Potassium channel 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Calcium/calmodulin-dependent protein kinase]]
[[Category: Drosophila melanogaster]]
[[Category: Drome]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Castro-Rodrigues, A F]]
[[Category: Castro-Rodrigues AF]]
[[Category: Morais-Cabral, J H]]
[[Category: Morais-Cabral JH]]
[[Category: Complex]]
[[Category: Potassium channel]]
[[Category: Protein kinase]]
[[Category: Transferase]]
Retrieved from "https://proteopedia.org/5hu3"