6sup: Difference between revisions

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<StructureSection load='6sup' size='340' side='right'caption='[[6sup]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='6sup' size='340' side='right'caption='[[6sup]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6sup]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SUP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6SUP FirstGlance]. <br>
<table><tr><td colspan='2'>[[6sup]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Photorhabdus_luminescens Photorhabdus luminescens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6SUP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6SUP FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Small_monomeric_GTPase Small monomeric GTPase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.5.2 3.6.5.2] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6sup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sup OCA], [http://pdbe.org/6sup PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6sup RCSB], [http://www.ebi.ac.uk/pdbsum/6sup PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6sup ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6sup FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6sup OCA], [https://pdbe.org/6sup PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6sup RCSB], [https://www.ebi.ac.uk/pdbsum/6sup PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6sup ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/Q8GF99_PHOLU Q8GF99_PHOLU] [https://www.uniprot.org/uniprot/Q8GF97_PHOLU Q8GF97_PHOLU] [https://www.uniprot.org/uniprot/CDC42_HUMAN CDC42_HUMAN] Plasma membrane-associated small GTPase which cycles between an active GTP-bound and an inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses. Involved in epithelial cell polarization processes. Regulates the bipolar attachment of spindle microtubules to kinetochores before chromosome congression in metaphase. Plays a role in the extension and maintenance of the formation of thin, actin-rich surface projections called filopodia. Mediates CDC42-dependent cell migration.<ref>PMID:14978216</ref> <ref>PMID:15642749</ref> <ref>PMID:17038317</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Small monomeric GTPase]]
[[Category: Photorhabdus luminescens]]
[[Category: Raunser, S]]
[[Category: Raunser S]]
[[Category: Roderer, D]]
[[Category: Roderer D]]
[[Category: Schubert, E]]
[[Category: Schubert E]]
[[Category: Sitsel, O]]
[[Category: Sitsel O]]
[[Category: Tc toxin]]
[[Category: Toxin]]
Retrieved from "https://proteopedia.org/6sup"