RNA Polymerase II: Difference between revisions
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<StructureSection load='1i6h' size='340' side='right' caption='RNA Polymerase II''> | <StructureSection load='1i6h' size='340' side='right' caption='RNA Polymerase II''> | ||
== Introduction == | == Introduction == | ||
[[ Image:Label RNA pol II (1).png|150px|right|thumb| RNAP II transcription process.]] | |||
RNA polymerase II (RNAP II) is an enzyme that transcribes protein-encoding genes, and it therefore is responsible for the synthesis of mRNA. There are three RNA polymerase enzymes found in eukaryotic nuclei but RNAP II is the most studied. RNAP II is a 550 kDa multi-protein complex that includes 12 subunits. Several transcription factors are used to bind promoters upstream of the start site and are necessary for joining RNAP II and DNA. Bound RNAP II transcribes DNA into a strand of messenger RNA. Messenger RNA (mRNA) is a single stranded RNA molecule that is complementary to the template strand of DNA. The mRNA stand transports genetic information from DNA to the ribosome, where it is used to specify the amino acid sequence for the production of proteins. | |||
RNA polymerase II (RNAP II) is an enzyme that transcribes protein-encoding genes, and it therefore is responsible for the synthesis of mRNA. Messenger RNA (mRNA) is a single stranded RNA molecule that is complementary to the template strand of DNA. The mRNA | |||
== Structural Components == | == Structural Components == | ||
