Sandbox Reserved 1561: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 28: | Line 28: | ||
<scene name='82/823085/Active_binding_sites/1'>Active Binding Sites</scene> Bap1 active site appears to be outside of the central cavity of the eight-bladed beta-propeller. There seems to be no catalytic triad associated within Bap1. | <scene name='82/823085/Active_binding_sites/1'>Active Binding Sites</scene> Bap1 active site appears to be outside of the central cavity of the eight-bladed beta-propeller. There seems to be no catalytic triad associated within Bap1. | ||
<scene name='82/823085/Key_bap1_residues/1'>Key Bap1 Residues</scene> | <scene name='82/823085/Key_bap1_residues/1'>Key Bap1 Residues</scene> include Asp348, Trp986, Tyr894, Trp948, Asn871, Asp853 and Phe850. These key residues are located the beta-prism of the Bap1 and are associated with carbohydrate bonding. | ||
<scene name='82/823085/Citrate_anion/2'>Citrate anion</scene>The citrate molecule in Bap1 binds in the carbohydrate-binding site in the beta-prism domains. Citrate is required to produce optimal crystal form due to the extensive crystal contacts in the area. | <scene name='82/823085/Citrate_anion/2'>Citrate anion</scene>The citrate molecule in Bap1 binds in the carbohydrate-binding site in the beta-prism domains. Citrate is required to produce optimal crystal form due to the extensive crystal contacts in the area. | ||
