6lf7: Difference between revisions

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'''Unreleased structure'''


The entry 6lf7 is ON HOLD
==Crystal structure of the complex of goat lactoperoxidase with hypothiocyanite and hydrogen peroxide at 1.79 A resolution.==
 
<StructureSection load='6lf7' size='340' side='right'caption='[[6lf7]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
Authors: Viswanathan, V., Tyagi, T.K., Singh, R.P., Singh, A.K., Singh, A., Bhushan, A., Sinha, M., Kaur, P., Sharma, S., Singh, T.P.
== Structural highlights ==
 
<table><tr><td colspan='2'>[[6lf7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Capra_hircus Capra hircus]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4n7a 4n7a]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LF7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6LF7 FirstGlance]. <br>
Description: Crystal structure of the complex of goat lactoperoxidase with hypothiocyanite and hydrogen peroxide at 1.79 A resolution.
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=IOD:IODIDE+ION'>IOD</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OSM:1-(OXIDOSULFANYL)METHANAMINE'>OSM</scene>, <scene name='pdbligand=PEO:HYDROGEN+PEROXIDE'>PEO</scene>, <scene name='pdbligand=SCN:THIOCYANATE+ION'>SCN</scene></td></tr>
[[Category: Unreleased Structures]]
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Peroxidase Peroxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.11.1.7 1.11.1.7] </span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6lf7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lf7 OCA], [http://pdbe.org/6lf7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6lf7 RCSB], [http://www.ebi.ac.uk/pdbsum/6lf7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6lf7 ProSAT]</span></td></tr>
</table>
== Function ==
[[http://www.uniprot.org/uniprot/PERL_CAPHI PERL_CAPHI]] Antimicrobial agent which utilizes hydrogen peroxide and thiocyanate (SCN) to generate the antimicrobial substance hypothiocyanous acid (HOSCN) (PubMed:10894086). May protect the udder from infection and promote growth in newborns. Inhibits growth of several fungi including A.niger, Trichoderma species, C.cassicola, P.meadii and C.salmonicolor (PubMed:10894086). Does not have anti-fungal activity towards C.albicans and Pythium species (PubMed:10894086). Inhibits growth of several Gram-positive bacteria including some Staphylococcus species and Gram-negative bacteria including E.coli, P.aeruginosa and some Salmonella species (PubMed:10894086).<ref>PMID:10894086</ref> 
== References ==
<references/>
__TOC__
</StructureSection>
[[Category: Capra hircus]]
[[Category: Large Structures]]
[[Category: Peroxidase]]
[[Category: Bhushan, A]]
[[Category: Bhushan, A]]
[[Category: Tyagi, T.K]]
[[Category: Kaur, P]]
[[Category: Sharma, S]]
[[Category: Singh, A]]
[[Category: Singh, A K]]
[[Category: Singh, R P]]
[[Category: Singh, T P]]
[[Category: Sinha, M]]
[[Category: Sinha, M]]
[[Category: Tyagi, T K]]
[[Category: Viswanathan, V]]
[[Category: Viswanathan, V]]
[[Category: Sharma, S]]
[[Category: Oxidoreductase]]
[[Category: Singh, R.P]]
[[Category: Peroxide family]]
[[Category: Singh, T.P]]
[[Category: Singh, A.K]]
[[Category: Singh, A]]
[[Category: Kaur, P]]
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