6cox: Difference between revisions
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[[Image:6cox.gif|left|200px]]<br /> | [[Image:6cox.gif|left|200px]]<br /><applet load="6cox" size="450" color="white" frame="true" align="right" spinBox="true" | ||
<applet load="6cox" size="450" color="white" frame="true" align="right" spinBox="true" | |||
caption="6cox, resolution 2.8Å" /> | caption="6cox, resolution 2.8Å" /> | ||
'''CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2) COMPLEXED WITH A SELECTIVE INHIBITOR, SC-558 IN I222 SPACE GROUP'''<br /> | '''CYCLOOXYGENASE-2 (PROSTAGLANDIN SYNTHASE-2) COMPLEXED WITH A SELECTIVE INHIBITOR, SC-558 IN I222 SPACE GROUP'''<br /> | ||
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==About this Structure== | ==About this Structure== | ||
6COX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with NAG, HEM and S58 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Prostaglandin-endoperoxide_synthase Prostaglandin-endoperoxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.1 1.14.99.1] | 6COX is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus] with NAG, HEM and S58 as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Prostaglandin-endoperoxide_synthase Prostaglandin-endoperoxide synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.14.99.1 1.14.99.1] Known structural/functional Sites: <scene name='pdbsite=ACE:SER 530 Is Acetylated By Aspirin (An Acetyl Group Is Cov ...'>ACE</scene>, <scene name='pdbsite=CAT:TYR 385 Is Believed To Be The Amino Acid That Abstracts ...'>CAT</scene>, <scene name='pdbsite=HEM:HIS 388 Is The Axial Ligand To The Heme'>HEM</scene> and <scene name='pdbsite=SUB:ARG 120 Is Believed To Anchor The Carboxylate Of Substra ...'>SUB</scene>. Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=6COX OCA]. | ||
==Reference== | ==Reference== | ||
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[[Category: prostaglandin synthase]] | [[Category: prostaglandin synthase]] | ||
''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on | ''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Tue Dec 18 20:47:08 2007'' | ||
