6d7a: Difference between revisions

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<StructureSection load='6d7a' size='340' side='right'caption='[[6d7a]], [[Resolution|resolution]] 1.13&Aring;' scene=''>
<StructureSection load='6d7a' size='340' side='right'caption='[[6d7a]], [[Resolution|resolution]] 1.13&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6d7a]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Toxgo Toxgo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D7A OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6D7A FirstGlance]. <br>
<table><tr><td colspan='2'>[[6d7a]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii Toxoplasma gondii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6D7A OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6D7A FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.13&#8491;</td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">PLP1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5811 TOXGO])</td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6d7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d7a OCA], [http://pdbe.org/6d7a PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6d7a RCSB], [http://www.ebi.ac.uk/pdbsum/6d7a PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6d7a ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6d7a FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6d7a OCA], [https://pdbe.org/6d7a PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6d7a RCSB], [https://www.ebi.ac.uk/pdbsum/6d7a PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6d7a ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PLP1_TOXGV PLP1_TOXGV] Pore-forming protein that promotes parasite exit from host cells: mediates formation of a pore in the parasitophorous vacuolar membrane, leading to membrane permeabilization, thereby facilitating parasite egress from host cells (PubMed:19095897, PubMed:29750191, PubMed:30513119). May also form a pore in the host plasma membrane (PubMed:19095897). Preferentially binds inner leaflet lipids, such as phosphatidylethanolamine (PE) or phosphatidylserine (PS) (PubMed:30513119).<ref>PMID:19095897</ref> <ref>PMID:29750191</ref> <ref>PMID:30513119</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 6d7a" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 6d7a" style="background-color:#fffaf0;"></div>
==See Also==
*[[Cytolysin 3D structures|Cytolysin 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Toxgo]]
[[Category: Toxoplasma gondii]]
[[Category: Bahr, C M.E]]
[[Category: Bahr CME]]
[[Category: Carruthers, V B]]
[[Category: Carruthers VB]]
[[Category: Guerra, A J]]
[[Category: Guerra AJ]]
[[Category: Koropatkin, N M]]
[[Category: Koropatkin NM]]
[[Category: Wawrzak, Z]]
[[Category: Wawrzak Z]]
[[Category: Beta-prism]]
[[Category: Lipid binding protein]]
[[Category: Perforin-like protein]]
[[Category: Pore forming protein]]
[[Category: Toxin]]
Retrieved from "https://proteopedia.org/6d7a"