6uuz: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6uuz is ~~ON HOLD~~

==Structure of ACLY in the presence of citrate and CoA==

~~Authors~~: ~~Xuepeng~~, W., ~~Ronen~~, M.

== Structural highlights ==

<table><tr><td colspan='2'>[[6uuz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UUZ OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UUZ FirstGlance].

~~Description~~: ~~Structure~~ of ~~ACLY~~ in the ~~presence~~ of citrate ~~and CoA~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/ATP_citrate_synthase ATP citrate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.8 2.3.3.8] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uuz OCA], [http://pdbe.org/6uuz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uuz RCSB], [http://www.ebi.ac.uk/pdbsum/6uuz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uuz ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/ACLY_HUMAN ACLY_HUMAN]] ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.<ref>PMID:23932781</ref>

== References ==

__TOC__

</StructureSection>

[[Category: ATP citrate synthase]]

[[Category: Large Structures]]

[[Category: Ronen, M]]

[[Category: Xuepeng, W]]

[[Category: ~~Ronen, M~~]]

[[Category: Enzyme]]

[[Category: Lyase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6uuz is ON HOLD
+==Structure of ACLY in the presence of citrate and CoA==
+<StructureSection load='6uuz' size='340' side='right'caption='[[6uuz]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
-Authors: Xuepeng, W., Ronen, M.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6uuz]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6UUZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6UUZ FirstGlance]. <br>
-Description: Structure of ACLY in the presence of citrate and CoA
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ATP_citrate_synthase ATP citrate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.3.8 2.3.3.8] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6uuz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6uuz OCA], [http://pdbe.org/6uuz PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6uuz RCSB], [http://www.ebi.ac.uk/pdbsum/6uuz PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6uuz ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/ACLY_HUMAN ACLY_HUMAN]] ATP citrate-lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Has a central role in de novo lipid synthesis. In nervous tissue it may be involved in the biosynthesis of acetylcholine.<ref>PMID:23932781</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: ATP citrate synthase]]
+[[Category: Large Structures]]
+[[Category: Ronen, M]]
 [[Category: Xuepeng, W]]
-[[Category: Ronen, M]]
+[[Category: Enzyme]]
+[[Category: Lyase]]