6kjd: Difference between revisions

From Proteopedia
Jump to navigationJump to search
← Older edit
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
OCA (talk | contribs)
Bots, Bureaucrats, journal, Administrators
3,331,613 edits
No edit summary
 
Line 3: Line 3:
<StructureSection load='6kjd' size='340' side='right'caption='[[6kjd]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
<StructureSection load='6kjd' size='340' side='right'caption='[[6kjd]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[6kjd]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KJD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6KJD FirstGlance]. <br>
<table><tr><td colspan='2'>[[6kjd]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Penicillium_rubens_Wisconsin_54-1255 Penicillium rubens Wisconsin 54-1255]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6KJD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=6KJD FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=144:TRIS-HYDROXYMETHYL-METHYL-AMMONIUM'>144</scene>, <scene name='pdbligand=LVA:(3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC+ACID'>LVA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.299&#8491;</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6kjd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kjd OCA], [http://pdbe.org/6kjd PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6kjd RCSB], [http://www.ebi.ac.uk/pdbsum/6kjd PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6kjd ProSAT]</span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=144:TRIS-HYDROXYMETHYL-METHYL-AMMONIUM'>144</scene>, <scene name='pdbligand=LVA:(3R,5R)-7-((1R,2R,6S,8R,8AS)-2,6-DIMETHYL-8-{[(2R)-2-METHYLBUTANOYL]OXY}-1,2,6,7,8,8A-HEXAHYDRONAPHTHALEN-1-YL)-3,5-DIHYDROXYHEPTANOIC+ACID'>LVA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=6kjd FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6kjd OCA], [https://pdbe.org/6kjd PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=6kjd RCSB], [https://www.ebi.ac.uk/pdbsum/6kjd PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=6kjd ProSAT]</span></td></tr>
</table>
</table>
== Function ==
[https://www.uniprot.org/uniprot/PCEST_PENRW PCEST_PENRW] Esterase that can hydrolyze the side chain of lovastatin to produce monacolin J (PubMed:28619444, PubMed:31839596). Is also able to hydrolyze the side chains of mevastatin and pravastatin, but not simvastatin (PubMed:28619444).<ref>PMID:28619444</ref> <ref>PMID:31839596</ref>
== References ==
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Liang, Y J]]
[[Category: Penicillium rubens Wisconsin 54-1255]]
[[Category: Lu, X F]]
[[Category: Liang YJ]]
[[Category: Family viii esterase]]
[[Category: Lu XF]]
[[Category: Hydrolase]]
[[Category: Lovastatin hydrolysis]]
[[Category: Monacolin j]]
[[Category: Simvastatin]]
Retrieved from "https://proteopedia.org/6kjd"