5elk: Difference between revisions
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<StructureSection load='5elk' size='340' side='right'caption='[[5elk]], [[Resolution|resolution]] 2.30Å' scene=''> | <StructureSection load='5elk' size='340' side='right'caption='[[5elk]], [[Resolution|resolution]] 2.30Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
<table><tr><td colspan='2'>[[5elk]] is a 2 chain structure with sequence from [ | <table><tr><td colspan='2'>[[5elk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5ELK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5ELK FirstGlance]. <br> | ||
</td></tr><tr id=' | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3Å</td></tr> | ||
<tr id=' | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | ||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5elk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5elk OCA], [https://pdbe.org/5elk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5elk RCSB], [https://www.ebi.ac.uk/pdbsum/5elk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5elk ProSAT]</span></td></tr> | |||
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | |||
</table> | </table> | ||
== Function == | == Function == | ||
[ | [https://www.uniprot.org/uniprot/UNK_MOUSE UNK_MOUSE] Sequence-specific RNA-binding protein which plays an important role in the establishment and maintenance of the early morphology of cortical neurons during embryonic development. Acts as a translation repressor and controls a translationally regulated cell morphology program to ensure proper structuring of the nervous system. Translational control depends on recognition of its binding element within target mRNAs which consists of a mandatory UAG trimer upstream of a U/A-rich motif. Associated with polysomes (PubMed:25737280).<ref>PMID:25737280</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
[[Category: | [[Category: Mus musculus]] | ||
[[Category: Murn | [[Category: Murn J]] | ||
[[Category: Patel | [[Category: Patel DJ]] | ||
[[Category: Shi | [[Category: Shi Y]] | ||
[[Category: Teplova | [[Category: Teplova M]] | ||
[[Category: Zarnack | [[Category: Zarnack K]] | ||