Sandbox Reserved 1098: Difference between revisions
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== Function == | == Function == | ||
The protein is a complex composed of the [[poly(ADP-ribosyl) glycohydrolase]] (PARG) and anthraquinone PDD00013907. The post-translational modifications of the PAR protein (poly ADP-ribose) are important for DNA stability. The PARG is used for one of these modifications, the hydrolyzation of specific ribose-ribose bonds present in PAR which leads to the degradation of PAR. | |||
PDD00013907 is an anthraquinone which is a polycyclic aromatic hydrocarbon usually used in biopesticides as a pest repellant. Here it is considered as a free ligand (of identification number on PDB: 7JB) that can bind to the PARG creating the protein complex 6HMM. | |||
=== Post-translational modifications to stabilize DNA === | === Post-translational modifications to stabilize DNA === | ||
=== The mechanism of | === The mechanism of the post-translational modifications === | ||
== Diseases and Relevance == | == Diseases and Relevance == | ||
