5tk0: Difference between revisions

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<StructureSection load='5tk0' size='340' side='right'caption='[[5tk0]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
<StructureSection load='5tk0' size='340' side='right'caption='[[5tk0]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5tk0]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TK0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5TK0 FirstGlance]. <br>
<table><tr><td colspan='2'>[[5tk0]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Gallus_gallus Gallus gallus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5TK0 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5TK0 FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.795&#8491;</td></tr>
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Lysozyme Lysozyme], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.17 3.2.1.17] </span></td></tr>
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5tk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tk0 OCA], [http://pdbe.org/5tk0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5tk0 RCSB], [http://www.ebi.ac.uk/pdbsum/5tk0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5tk0 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5tk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5tk0 OCA], [https://pdbe.org/5tk0 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5tk0 RCSB], [https://www.ebi.ac.uk/pdbsum/5tk0 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5tk0 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK]] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref> 
[https://www.uniprot.org/uniprot/LYSC_CHICK LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.<ref>PMID:22044478</ref>  
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
3D printed micrometer-scale polymer mounts for single crystal analysis have been prepared by photopolymerization using digital light projection stereolithography (DLP-SLA), with a commercially available digital light projection stereolithography printer (US$4000) and 3DM-ABS resin (US$150 per liter). The polymer mounts were prepared in batches of 49 in 1 h 15 min, which allowed for rapid prototyping and testing of new crystal mounting designs, with a resin cost of 0.2 cent US per mount. The suitability of the 3D printed mounts for single crystal crystallography has been demonstrated through their use in Cu Kalpha X-ray diffraction experiments of Rochelle salt (sodium potassium tartrate), the protein lysozyme, and has been employed for routine crystallographic analysis of organic and inorganic materials.
 
3D Printed Micrometer-Scale Polymer Mounts for Single Crystal Analysis.,Macdonald NP, Bunton GL, Park AY, Breadmore MC, Kilah NL Anal Chem. 2017 Mar 30. doi: 10.1021/acs.analchem.7b00443. PMID:28319372<ref>PMID:28319372</ref>
 
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
<div class="pdbe-citations 5tk0" style="background-color:#fffaf0;"></div>


==See Also==
==See Also==
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[[Category: Gallus gallus]]
[[Category: Gallus gallus]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Lysozyme]]
[[Category: Breadmore MC]]
[[Category: Breadmore, M C]]
[[Category: Bunton G]]
[[Category: Bunton, G]]
[[Category: Kilah NL]]
[[Category: Kilah, N L]]
[[Category: MacDonald N]]
[[Category: MacDonald, N]]
[[Category: Park AY]]
[[Category: Park, A Y]]
[[Category: Hydrolase]]

Revision as of 15:41, 6 March 2024

Lysozyme structure collected with 3D printed polymer mounts

5tk0, resolution 1.79Å

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