6lk0: Difference between revisions
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==Crystal structure of human wild type TRIP13== | |||
<StructureSection load='6lk0' size='340' side='right'caption='[[6lk0]], [[Resolution|resolution]] 2.60Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6lk0]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LK0 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6LK0 FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6lk0 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6lk0 OCA], [http://pdbe.org/6lk0 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6lk0 RCSB], [http://www.ebi.ac.uk/pdbsum/6lk0 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6lk0 ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
[[Category: | == Function == | ||
[[http://www.uniprot.org/uniprot/PCH2_HUMAN PCH2_HUMAN]] Plays a key role in chromosome recombination and chromosome structure development during meiosis. Required at early steps in meiotic recombination that leads to non-crossovers pathways. Also needed for efficient completion of homologous synapsis by influencing crossover distribution along the chromosomes affecting both crossovers and non-crossovers pathways. Also required for development of higher-order chromosome structures and is needed for synaptonemal-complex formation. In males, required for efficient synapsis of the sex chromosomes and for sex body formation. Promotes early steps of the DNA double-strand breaks (DSBs) repair process upstream of the assembly of RAD51 complexes. Required for depletion of HORMAD1 and HORMAD2 from synapsed chromosomes (By similarity). | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Chang, S]] | |||
[[Category: Chen, G]] | |||
[[Category: Gao, L]] | |||
[[Category: Hu, L]] | [[Category: Hu, L]] | ||
[[Category: | [[Category: Huang, J]] | ||
[[Category: | [[Category: Kong, Y]] | ||
[[Category: Li, B]] | |||
[[Category: | |||
[[Category: Lian, F]] | [[Category: Lian, F]] | ||
[[Category: Mao, Z]] | [[Category: Mao, Z]] | ||
[[Category: Shi, J]] | [[Category: Shi, J]] | ||
[[Category: | [[Category: Sun, X]] | ||
[[Category: Tao, Y]] | |||
[[Category: Tricot, G]] | |||
[[Category: Wang, Y]] | |||
[[Category: Wu, X]] | |||
[[Category: Xiao, W]] | |||
[[Category: Xie, Y]] | |||
[[Category: Xu, H]] | [[Category: Xu, H]] | ||
[[Category: | [[Category: Xu, Z]] | ||
[[Category: | [[Category: Xue, H]] | ||
[[Category: Yu, D]] | [[Category: Yu, D]] | ||
[[Category: | [[Category: Zhan, F]] | ||
[[Category: | [[Category: Zhang, N]] | ||
[[Category: | [[Category: Zhu, W]] | ||
[[Category: | [[Category: Aaa+ atpase]] | ||
[[Category: | [[Category: Atp-bound]] | ||
[[Category: Conformation dynamic]] | |||
[[Category: Hexamer helical filament]] | |||
[[Category: Oncoprotein]] | |||
Revision as of 16:09, 22 January 2020
Crystal structure of human wild type TRIP13
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