1a9l: Difference between revisions

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[[Image:1a9l.~~jpg~~|left|200px]]

[[Image:1a9l.png|left|200px]]

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~~'''~~SOLUTION STRUCTURE OF A SUBSTRATE FOR THE ARCHAEAL PRE-TRNA SPLICING ENDONUCLEASES: THE BULGE-HELIX-BULGE MOTIF, NMR, 12 STRUCTURES~~'''~~

===SOLUTION STRUCTURE OF A SUBSTRATE FOR THE ARCHAEAL PRE-TRNA SPLICING ENDONUCLEASES: THE BULGE-HELIX-BULGE MOTIF, NMR, 12 STRUCTURES===

~~==Overview==~~

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The ~~structure of~~ the ~~bulge-helix-bulge motif that constitutes~~ the ~~intron~~/~~exon splice site in H~~. ~~volcanii pre-tRNATrp has been determined by NMR spectroscopy~~. ~~The conformations of the two 3 nt bulges~~, where ~~the pre-tRNA~~ is ~~cleaved, are stabilized by stacking interactions between bulge nucleotides and bases in~~ the ~~adjacent Watson-Crick helices and by a network of backbone hydrogen bonds~~. ~~Both bulges are presented on the same minor groove face of the central 4 bp helix, and the overall structure has approximate two~~-~~fold symmetry, which makes it well~~-~~suited for attack by archaeal splicing endonucleases, which are symmetric dimers.~~

The line below this paragraph, {{ABSTRACT_PUBMED_9660971}}, adds the Publication Abstract to the page

(as it appears on PubMed at http://www.pubmed.gov), where 9660971 is the PubMed ID number.

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==About this Structure==

Full ~~crystallographic~~ information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A9L OCA].

Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A9L OCA].

==Reference==

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[[Category: Ribonucleic acid]]

[[Category: Rna structure]]

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on ~~Fri May 2 10~~:00:58 2008''

''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:26:13 2008''

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-[[Image:1a9l.jpg|left|200px]]
+{{Seed}}
+[[Image:1a9l.png|left|200px]]
 <!--
@@ Line 9: / Line 10: @@
 {{STRUCTURE_1a9l|  PDB=1a9l  |  SCENE=  }}
-'''SOLUTION STRUCTURE OF A SUBSTRATE FOR THE ARCHAEAL PRE-TRNA SPLICING ENDONUCLEASES: THE BULGE-HELIX-BULGE MOTIF, NMR, 12 STRUCTURES'''
+===SOLUTION STRUCTURE OF A SUBSTRATE FOR THE ARCHAEAL PRE-TRNA SPLICING ENDONUCLEASES: THE BULGE-HELIX-BULGE MOTIF, NMR, 12 STRUCTURES===
-==Overview==
+<!--
-The structure of the bulge-helix-bulge motif that constitutes the intron/exon splice site in H. volcanii pre-tRNATrp has been determined by NMR spectroscopy. The conformations of the two 3 nt bulges, where the pre-tRNA is cleaved, are stabilized by stacking interactions between bulge nucleotides and bases in the adjacent Watson-Crick helices and by a network of backbone hydrogen bonds. Both bulges are presented on the same minor groove face of the central 4 bp helix, and the overall structure has approximate two-fold symmetry, which makes it well-suited for attack by archaeal splicing endonucleases, which are symmetric dimers.
+The line below this paragraph, {{ABSTRACT_PUBMED_9660971}}, adds the Publication Abstract to the page
+(as it appears on PubMed at http://www.pubmed.gov), where 9660971 is the PubMed ID number.
+-->
+{{ABSTRACT_PUBMED_9660971}}
 ==About this Structure==
-Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A9L OCA].
+Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A9L OCA].
 ==Reference==
@@ Line 28: / Line 32: @@
 [[Category: Ribonucleic acid]]
 [[Category: Rna structure]]
-''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May  2 10:00:58 2008''
+''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:26:13 2008''