Sandbox Reserved 1098: Difference between revisions

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This protein has four principal domains on a <scene name='82/829351/Single_chain/1'>single peptide chain</scene>: a A-domain, a catalytic domain and two substrate binding domains[http://www.uniprot.org/uniprot/Q86W56].

The first 456 amino acids of the peptide chain form the <scene name='82/829351/A_domain/1'>A-domain</scene>. Then from 610 to 795 amino acids is located the <scene name='82/829351/Catalytic_domain/1'>catalytic domain</scene>. This catalytic domain can binding with other proteins with two amino acids (the 726 and 727 amino acids). Next the second substrate binding domain is located from the 869 th to the 874th amino acids. [http://www.uniprot.org/uniprot/Q86W56]

The first 456 amino acids of the peptide chain form the <scene name='82/829351/A_domain/1'>A-domain</scene>. Then from 610 to 795 amino acids is located the <scene name='82/829351/Catalytic_domain/1'>catalytic domain</scene>. This catalytic domain can binding with other proteins with <scene name='82/829351/Substrat_-_catalytic_domain/1'>two amino acids</scene> (the 726 and 727 amino acids). Next the second substrate binding domain is located from the 869 th to the 874th amino acids. [http://www.uniprot.org/uniprot/Q86W56]

So, most of the amino acids form the A-domain and the catzlytic domain and only few amino acids (8 a.a) make links with other proteins. Moreover, the ligand 7JB can bind the protein on the <scene name='82/829351/Liason_7jb/1'>754, 758, 792 and 795 amino acids</scene>. These amino acids are located on a helix and on a beta sheet. [https://www.rcsb.org/pdb/explore/remediatedSequence.do?structureId=6HMM]

Sandbox Reserved 1098: Difference between revisions

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 This protein has four principal domains on a <scene name='82/829351/Single_chain/1'>single peptide chain</scene>: a A-domain, a catalytic domain and two substrate binding domains[http://www.uniprot.org/uniprot/Q86W56].
-The first 456 amino acids of the peptide chain form the <scene name='82/829351/A_domain/1'>A-domain</scene>. Then from 610 to 795 amino acids is located the <scene name='82/829351/Catalytic_domain/1'>catalytic domain</scene>. This catalytic domain can binding with other proteins with two amino acids (the 726 and 727 amino acids). Next the second substrate binding domain is located from the 869 th to the 874th amino acids. [http://www.uniprot.org/uniprot/Q86W56]
+The first 456 amino acids of the peptide chain form the <scene name='82/829351/A_domain/1'>A-domain</scene>. Then from 610 to 795 amino acids is located the <scene name='82/829351/Catalytic_domain/1'>catalytic domain</scene>. This catalytic domain can binding with other proteins with <scene name='82/829351/Substrat_-_catalytic_domain/1'>two amino acids</scene> (the 726 and 727 amino acids). Next the second substrate binding domain is located from the 869 th to the 874th amino acids. [http://www.uniprot.org/uniprot/Q86W56]
 So, most of the amino acids form the A-domain and the catzlytic domain and only few amino acids (8 a.a) make links with other proteins. Moreover, the ligand 7JB can bind the protein on the <scene name='82/829351/Liason_7jb/1'>754, 758, 792 and 795 amino acids</scene>. These amino acids are located on a helix and on a beta sheet. [https://www.rcsb.org/pdb/explore/remediatedSequence.do?structureId=6HMM]