Sandbox Reserved 1098: Difference between revisions

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This protein has four principal domains on a <scene name='82/829351/Single_chain/1'>single peptide chain</scene>: a A-domain, a catalytic domain and two substrate binding domains[http://www.uniprot.org/uniprot/Q86W56].

The first 456 amino acids of the peptide chain form the <scene name='82/829351/A_domain/1'>A-domain</scene>. Then from 610 to 795 amino acids is located the <scene name='82/829351/Catalytic_domain/1'>catalytic domain</scene>. This catalytic domain can binding with other proteins with <scene name='82/829351/Substrat_-_catalytic_domain/1'>two amino acids</scene> (the 726 and 727 amino acids). Next the second substrate binding domain is located from the 869 th to the 874th amino acids. [http://www.uniprot.org/uniprot/Q86W56]

The first 456 amino acids of the peptide chain form the <scene name='82/829351/A_domain/1'>A-domain</scene>. Then from 610 to 795 amino acids is located the <scene name='82/829351/Catalytic_domain/1'>catalytic domain</scene>. This catalytic domain can binding with other proteins with <scene name='82/829351/Substrat_-_catalytic_domain/1'>two amino acids</scene> (the 726 and 727 amino acids). Next <scene name='82/829351/Subtrat_jonction_domain_2/1'>the second substrate binding domain</scene> is located from the 869 th to the 874th amino acids. [http://www.uniprot.org/uniprot/Q86W56]

So, most of the amino acids form the A-domain and the catzlytic domain and only few amino acids (8 a.a) make links with other proteins. Moreover, the ligand 7JB can bind the protein on the <scene name='82/829351/Liason_7jb/1'>754, 758, 792 and 795 amino acids</scene>. These amino acids are located on a helix and on a beta sheet. [https://www.rcsb.org/pdb/explore/remediatedSequence.do?structureId=6HMM]

Sandbox Reserved 1098: Difference between revisions

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 This protein has four principal domains on a <scene name='82/829351/Single_chain/1'>single peptide chain</scene>: a A-domain, a catalytic domain and two substrate binding domains[http://www.uniprot.org/uniprot/Q86W56].
-The first 456 amino acids of the peptide chain form the <scene name='82/829351/A_domain/1'>A-domain</scene>. Then from 610 to 795 amino acids is located the <scene name='82/829351/Catalytic_domain/1'>catalytic domain</scene>. This catalytic domain can binding with other proteins with <scene name='82/829351/Substrat_-_catalytic_domain/1'>two amino acids</scene> (the 726 and 727 amino acids). Next the second substrate binding domain is located from the 869 th to the 874th amino acids. [http://www.uniprot.org/uniprot/Q86W56]
+The first 456 amino acids of the peptide chain form the <scene name='82/829351/A_domain/1'>A-domain</scene>. Then from 610 to 795 amino acids is located the <scene name='82/829351/Catalytic_domain/1'>catalytic domain</scene>. This catalytic domain can binding with other proteins with <scene name='82/829351/Substrat_-_catalytic_domain/1'>two amino acids</scene> (the 726 and 727 amino acids). Next <scene name='82/829351/Subtrat_jonction_domain_2/1'>the second substrate binding domain</scene> is located from the 869 th to the 874th amino acids. [http://www.uniprot.org/uniprot/Q86W56]
 So, most of the amino acids form the A-domain and the catzlytic domain and only few amino acids (8 a.a) make links with other proteins. Moreover, the ligand 7JB can bind the protein on the <scene name='82/829351/Liason_7jb/1'>754, 758, 792 and 795 amino acids</scene>. These amino acids are located on a helix and on a beta sheet. [https://www.rcsb.org/pdb/explore/remediatedSequence.do?structureId=6HMM]