Sandbox Reserved 1096: Difference between revisions
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*Stable head to tail dimer | *Stable head to tail dimer | ||
*Monomer comprised of 2 immunoglobulin-like domains + C-term catalytic domain calcium binding site C2-5 are unoccupied in apoPAD2 but electron density on C1 and C6 so those are occupied. | *Monomer comprised of 2 immunoglobulin-like domains + C-term catalytic domain calcium binding site C2-5 are unoccupied in apoPAD2 but electron density on C1 and C6 so those are occupied. | ||
*Same fold as apoenzyme except C3-5 are occupied even though just one site unoccupied, the structure is not catalytically competent, it is explained because the active site nucleophile C647, is just 12 angstrom away from the catalytic center. | *Same fold as apoenzyme except C3-5 are occupied even though just one site unoccupied, the structure is not catalytically competent, it is explained because the active site nucleophile C647, is just 12 angstrom away from the catalytic center. | ||
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==='''Catalysis of deimination'''=== | ==='''Catalysis of deimination'''=== | ||
== Citrullination of Arginine residues == | == Citrullination of Arginine residues == | ||
