Sandbox Reserved 1104: Difference between revisions
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=====Diagnostic analysis and treatment===== | =====Diagnostic analysis and treatment===== | ||
Bilirubin oxidase is used for diagnostic analysis of bilirubin in serum during medical examinations. It is useful in the field of clinical pathology for the diagnosis and treatment of jaundice and hyperbilirubinemia. It is used to determine two types of bilirubin: glucuronide-conjugated and unconjugated bilirubin separately.<ref>MP Biomedicals, Bilirubin Oxidase [https://www.mpbio.com/0219000010-bilirubin-oxidase-cf]</ref> Conjugated bilirubin can be quantitatively determined from a decrease in the absorbance at 450 nm caused by conjugated bilirubin oxidisation by bilirubin oxidase. The conjugated bilirubin values help for the evaluation of jaundice.<ref>PMID: 10645982</ref> | Bilirubin oxidase is used for diagnostic analysis of bilirubin in serum during medical examinations. It is useful in the field of clinical pathology for the diagnosis and treatment of jaundice and hyperbilirubinemia. It is used to determine two types of bilirubin: glucuronide-conjugated and unconjugated bilirubin separately.<ref>MP Biomedicals, Bilirubin Oxidase [https://www.mpbio.com/0219000010-bilirubin-oxidase-cf]</ref> Conjugated bilirubin can be quantitatively determined from a decrease in the absorbance at 450 nm caused by conjugated bilirubin oxidisation by bilirubin oxidase. The conjugated bilirubin values help for the evaluation of jaundice.<ref>PMID: 10645982</ref> ) Finally, the addition of bilirubin to the cells has toxic effects, and the addition of bilirubin oxidase can reverse these effects. Thus, hyperbilirubinemia in newborn infants may be prevented by administering polyethylene glycol-conjugated bilirubin oxidase.<ref>PMID: 2399262</ref> | ||
