Sandbox Reserved 1092: Difference between revisions
From Proteopedia
Jump to navigationJump to search
Morgane Mura (talk | contribs) No edit summary |
Morgane Mura (talk | contribs) No edit summary |
||
| Line 1: | Line 1: | ||
{{Sandbox_ESBS_2019}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | {{Sandbox_ESBS_2019}}<!-- PLEASE ADD YOUR CONTENT BELOW HERE --> | ||
=5JI1 : Myostatin (GDF8)= | =5JI1 : Myostatin (GDF8)= | ||
<StructureSection load='5JI1' size='340' side='right' caption='Caption for this structure' scene=''> | |||
</StructureSection> | |||
= Function = | = Function = | ||
| Line 56: | Line 59: | ||
During the research trials, a monoclonal antibiotic was injected to mice during 10 weeks and the results showed that the muscle strength and the muscle fiber diameter increased. Moreover, the expression of the markers of muscle fibrosis reduced. However, myostatin does not cure the disease because no change was noticed the in intra-nuclear inclusion density, which is a characteristic of OPMD spread. It is for now only a solution to treat the symptom. | During the research trials, a monoclonal antibiotic was injected to mice during 10 weeks and the results showed that the muscle strength and the muscle fiber diameter increased. Moreover, the expression of the markers of muscle fibrosis reduced. However, myostatin does not cure the disease because no change was noticed the in intra-nuclear inclusion density, which is a characteristic of OPMD spread. It is for now only a solution to treat the symptom. | ||
In other cases, it is also possible to introduce follistatin <ref> PMID:19644449</ref> to block myostatin because they will form a complex which will stop the myostatin' action. | In other cases, it is also possible to introduce follistatin <ref> PMID:19644449</ref> to block myostatin because they will form a complex which will stop the myostatin' action. | ||
