Sandbox TYRP1: Difference between revisions
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According to crystal knowledges, it is said that TYRP1 and TYR can bind the same substrats. | |||
The three enzymes have several sites of N-glycosylation which are important for their maturation, two of these sites are shared by the three enzymes. TYRP1 and 2 have both six sites and among them, four are exactly the same. <ref name="Xlai"/> | The three enzymes have several sites of N-glycosylation which are important for their maturation, two of these sites are shared by the three enzymes. TYRP1 and 2 have both six sites and among them, four are exactly the same. <ref name="Xlai"/> | ||
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==== Differences: ==== | ==== Differences: ==== | ||
The main difference between these three enzyme is the nature of metal ions they bind on the active site. TYRP1 and TYRP2 bind two zinc ions whereas TYR binds two copper ions. | The main difference between these three enzyme is the nature of metal ions they bind on the active site. TYRP1 and TYRP2 bind two zinc ions whereas TYR binds two copper ions. | ||
Contrary to TYRP1 and TYRP2, TYR contains six sites of N- | Contrary to TYRP1 and TYRP2, TYR contains six sites of N-glycosylation. | ||
