Sandbox Reserved 1101: Difference between revisions
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::*''Van der Waals'' | ::*''Van der Waals'' | ||
<scene name='82/829354/T47b-i48a-a51a-l69a/1'>T47B engage in Van Der Waals contacts with I48A, A51A and L69A residues</scene>. Also, <scene name='82/829354/M55b-d40a-t43a/2'>M55B is commited in Van Der Waals interactions with D40A and T43A</scene>. | <scene name='82/829354/T47b-i48a-a51a-l69a/1'>T47B engage in Van Der Waals contacts with I48A, A51A and L69A residues</scene>. Also, <scene name='82/829354/M55b-d40a-t43a/2'>M55B is commited in Van Der Waals interactions with D40A and T43A</scene>. In subunits H2A and H2B, T47A and A51B engage in a Van Der Waals interaction of 4,1 Å, and that contribute to the plasticity of the dimer interface. | ||
::*''Hydrogen bonds and electrostatic interactions'' | ::*''Hydrogen bonds and electrostatic interactions'' | ||
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On the other side on the dimer interface, there are also other specific contacts but distinct due to the different topology. But residues T47A, K54A and M55A are less buried than their counterparts in subunit A in particularly K54A which doesn’t engage any interaction. | On the other side on the dimer interface, there are also other specific contacts but distinct due to the different topology. But residues T47A, K54A and M55A are less buried than their counterparts in subunit A in particularly K54A which doesn’t engage any interaction. | ||
::*''Hydrophobic pockets'' | |||
Then, in subunits H5A and H5B, M126A and F127A also buried at the dimer interface, insert into hydrophobic pockets formed by S122B, L123B and M71B, S75B, E119B and I120B respectively. | |||
====pH-dependent mechanism==== | ====pH-dependent mechanism==== | ||
