Sandbox Reserved 1094: Difference between revisions
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== Function == | == Function == | ||
'''G6PD''' plays an important role in the metabolism of L.''mesenteroides''. | '''G6PD''' plays an important role in the metabolism of L.''mesenteroides''. | ||
L.''mesenteroides'' is a facultactively anaerobic micro-organism which metabolizes glucose to generate lactic acid, ethanol but also carbon dioxyde. | |||
This glucose metabolic process (glycolysis and pentose phosphate pathway) is catalysed by '''G6PD'''. During this process, [[NADH]] is synthesised and used in the heterolactic fermentation and the biosynthesis of fatty acids. | This glucose metabolic process (glycolysis and pentose phosphate pathway) is catalysed by '''G6PD'''. During this process, [[NADH]] is synthesised and used in the heterolactic fermentation and the biosynthesis of fatty acids. | ||
The protein '''G6PD''' also has a role in protecting cells from destruction as it produces the co-factor NADPH which plays a role in protecting cells from reactive oxygen species <ref>PMID: 20608171</ref>. | The protein '''G6PD''' also has a role in protecting cells from destruction as it produces the co-factor NADPH which plays a role in protecting cells from reactive oxygen species <ref>PMID: 20608171</ref>. | ||
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It is coded by the '''G6PD''' gene (1461 nucleotides)<ref>GeneID:29577449</ref>. | It is coded by the '''G6PD''' gene (1461 nucleotides)<ref>GeneID:29577449</ref>. | ||
It has in total 2 chains. In the link below, these two chains are represented by one unique sequence entity. | It has in total 2 chains. In the link below, these two chains are represented by one unique sequence entity. | ||
<font color='grey'>External resource</font> : click on [https://www.rcsb.org/pdb/explore/remediatedSequence.do?structureId=1DPG] to see the graphical representation. | |||
<font color='grey'>External resource</font> : click on [https://www.rcsb.org/pdb/explore/remediatedSequence.do?structureId=1DPG/RCSB] to see the graphical representation. | |||
== Catalytic activity == | == Catalytic activity == | ||
