Sandbox Reserved 1109: Difference between revisions
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<StructureSection load='6flt' size='340' side='right'caption='[[6flt]], [[Resolution|resolution]] 3.42Å' scene=''> | <StructureSection load='6flt' size='340' side='right'caption='[[6flt]], [[Resolution|resolution]] 3.42Å' scene=''> | ||
α-synuclein is a protein encoded by the SNCA gene in humans and belongs to the family of synuclein proteins that also consist of beta and gamma- synuclein. It is present in large quantities in the brain and in comparatively smaller quantities in other tissues in the body. α-synuclein is mainly present at the presynaptic terminals in the neuronal mitochondria and comprises of 1% of the total cytosolic protein in the nervous system. It is mainly related to neurodegenerative diseases in humans. | α-synuclein is a protein encoded by the SNCA gene in humans and belongs to the family of synuclein proteins that also consist of beta and gamma- synuclein. It is present in large quantities in the brain and in comparatively smaller quantities in other tissues in the body. α-synuclein is mainly present at the presynaptic terminals in the neuronal mitochondria and comprises of 1% of the total cytosolic protein in the nervous system. It is mainly related to neurodegenerative diseases in humans. </11> | ||
== Function == | == Function == | ||
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</StructureSection> | </StructureSection> | ||
== References == | == References == | ||
Bendor, J. T., Logan, T. P., & Edwards, R. H. (2013). The function of α-synuclein. Neuron, 79(6), 1044–1066. doi:10.1016/j.neuron.2013.09.004 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866954/ | <11> Bendor, J. T., Logan, T. P., & Edwards, R. H. (2013). The function of α-synuclein. Neuron, 79(6), 1044–1066. doi:10.1016/j.neuron.2013.09.004 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3866954/ | ||
Cold Spring Harb Perspect Med 2012;4:a009399, Stefanis L.a-Synuclein in Parkinson’s Disease . | Cold Spring Harb Perspect Med 2012;4:a009399, Stefanis L.a-Synuclein in Parkinson’s Disease . | ||
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281589/pdf/cshperspectmed-PKD-a009399.pdf | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3281589/pdf/cshperspectmed-PKD-a009399.pdf | ||
