6ln2: Difference between revisions
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==Crystal structure of full length human GLP1 receptor in complex with Fab fragment (Fab7F38)== | |||
<StructureSection load='6ln2' size='340' side='right'caption='[[6ln2]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ln2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6LN2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6LN2 FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=97Y:N-{4-[(R)-(3,3-DIMETHYLCYCLOBUTYL)({6-[4-(TRIFLUOROMETHYL)-1H-IMIDAZOL-1-YL]PYRIDIN-3-YL}AMINO)METHYL]BENZENE-1-CARBONYL}-BETA-ALANINE'>97Y</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ln2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ln2 OCA], [http://pdbe.org/6ln2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ln2 RCSB], [http://www.ebi.ac.uk/pdbsum/6ln2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ln2 ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/GLP1R_HUMAN GLP1R_HUMAN]] This is a receptor for glucagon-like peptide 1. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Han, G W]] | |||
[[Category: Hang, K]] | |||
[[Category: Hanson, M]] | |||
[[Category: Jiang, H]] | |||
[[Category: Laursen, M]] | |||
[[Category: Lin, G]] | |||
[[Category: Reedtz-Runge, S]] | |||
[[Category: Ren, Q]] | |||
[[Category: Roed, N K]] | |||
[[Category: Song, G]] | |||
[[Category: Stevens, R C]] | |||
[[Category: Wang, M]] | |||
[[Category: Wu, F]] | |||
[[Category: Wu, L]] | |||
[[Category: Yang, L]] | |||
[[Category: Class b]] | |||
[[Category: Fab7f38]] | |||
[[Category: Full length human glp1 receptor]] | |||
[[Category: Lcp]] | |||
[[Category: Membrane protein]] | |||
[[Category: Nam pf06372222]] | |||
[[Category: Tmd]] | |||
Revision as of 09:41, 18 March 2020
Crystal structure of full length human GLP1 receptor in complex with Fab fragment (Fab7F38)
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