6tkv: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6tkv ~~is ON HOLD~~

==Crystal structure of the human FUT8 in complex with GDP and a biantennary complex N-glycan==

~~Authors~~: ~~Garcia~~-~~Garcia, A~~., ~~Ceballos~~-~~Laita~~, L., ~~Serna~~, L., ~~Artschwager~~, R., ~~Reichardt~~, N.C., ~~Corzana, F~~.~~, Hurtado~~-~~Guerrero, R~~.

== Structural highlights ==

<table><tr><td colspan='2'>[[6tkv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TKV OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TKV FirstGlance].

~~Description~~: ~~Crystal structure~~ of ~~a glycosyltransferase complexed~~ to the ~~donor and acceptor substrate~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Glycoprotein_6-alpha-L-fucosyltransferase Glycoprotein 6-alpha-L-fucosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.68 2.4.1.68] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tkv OCA], [http://pdbe.org/6tkv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tkv RCSB], [http://www.ebi.ac.uk/pdbsum/6tkv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tkv ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/FUT8_HUMAN FUT8_HUMAN]] Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.<ref>PMID:9133635</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Glycoprotein 6-alpha-L-fucosyltransferase]]

[[Category: Large Structures]]

[[Category: Artschwager, R]]

[[Category: Ceballos-Laita, L]]

[[Category: Corzana, F]]

[[Category: Garcia-Garcia, A]]

[[Category: Hurtado-Guerrero, R]]

~~[[Category: Garcia-Garcia, A]]~~

[[Category: Reichardt, N C]]

[[Category: Reichardt, N.C]]

[[Category: Serna, L]]

[[Category: ~~Corzana, F~~]]

[[Category: Acceptor substrate]]

[[Category: ~~Artschwager, R~~]]

[[Category: Catalysis]]

[[Category: Glycosyltransferase]]

[[Category: Sugar binding protein]]

[[Category: Sugar nucleotide]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6tkv is ON HOLD
+==Crystal structure of the human FUT8 in complex with GDP and a biantennary complex N-glycan==
+<StructureSection load='6tkv' size='340' side='right'caption='[[6tkv]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
-Authors: Garcia-Garcia, A., Ceballos-Laita, L., Serna, L., Artschwager, R., Reichardt, N.C., Corzana, F., Hurtado-Guerrero, R.
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6tkv]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6TKV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6TKV FirstGlance]. <br>
-Description: Crystal structure of a glycosyltransferase complexed to the donor and acceptor substrate
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MAN:ALPHA-D-MANNOSE'>MAN</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glycoprotein_6-alpha-L-fucosyltransferase Glycoprotein 6-alpha-L-fucosyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.4.1.68 2.4.1.68] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6tkv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6tkv OCA], [http://pdbe.org/6tkv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6tkv RCSB], [http://www.ebi.ac.uk/pdbsum/6tkv PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6tkv ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/FUT8_HUMAN FUT8_HUMAN]] Catalyzes the addition of fucose in alpha 1-6 linkage to the first GlcNAc residue, next to the peptide chains in N-glycans.<ref>PMID:9133635</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Glycoprotein 6-alpha-L-fucosyltransferase]]
+[[Category: Large Structures]]
+[[Category: Artschwager, R]]
 [[Category: Ceballos-Laita, L]]
+[[Category: Corzana, F]]
+[[Category: Garcia-Garcia, A]]
 [[Category: Hurtado-Guerrero, R]]
-[[Category: Garcia-Garcia, A]]
+[[Category: Reichardt, N C]]
-[[Category: Reichardt, N.C]]
 [[Category: Serna, L]]
-[[Category: Corzana, F]]
+[[Category: Acceptor substrate]]
-[[Category: Artschwager, R]]
+[[Category: Catalysis]]
+[[Category: Glycosyltransferase]]
+[[Category: Sugar binding protein]]
+[[Category: Sugar nucleotide]]