6irl: Difference between revisions
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The | ==Crystal structure of 8-mer peptide from avian influenza H5N1 virus in complex with BF2*1501== | ||
<StructureSection load='6irl' size='340' side='right'caption='[[6irl]], [[Resolution|resolution]] 2.10Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6irl]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6IRL OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6IRL FirstGlance]. <br> | |||
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6irl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6irl OCA], [http://pdbe.org/6irl PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6irl RCSB], [http://www.ebi.ac.uk/pdbsum/6irl PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6irl ProSAT]</span></td></tr> | |||
[[Category: | </table> | ||
== Function == | |||
[[http://www.uniprot.org/uniprot/PA_I01A3 PA_I01A3]] Plays an essential role in viral RNA transcription and replication by forming the heterotrimeric polymerase complex together with PB1 and PB2 subunits. The complex transcribes viral mRNAs by using a unique mechanism called cap-snatching. It consists in the hijacking and cleavage of host capped pre-mRNAs. These short capped RNAs are then used as primers for viral mRNAs. The PB2 subunit is responsible for the binding of the 5' cap of cellular pre-mRNAs which are subsequently cleaved after 10-13 nucleotides by the PA subunit that carries the endonuclease activity.[HAMAP-Rule:MF_04063] [[http://www.uniprot.org/uniprot/B2MG_CHICK B2MG_CHICK]] Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Xiao, L]] | |||
[[Category: Zhang, L]] | |||
[[Category: 8-mer]] | |||
[[Category: Avian influenza virus]] | |||
[[Category: Chicken]] | |||
[[Category: Epitope]] | |||
[[Category: H5n1]] | |||
[[Category: Immune system]] | |||
[[Category: Mhc class i]] | |||
Revision as of 09:37, 18 March 2020
Crystal structure of 8-mer peptide from avian influenza H5N1 virus in complex with BF2*1501
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