6os2: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6os2 is ~~ON HOLD until Paper Publication~~

==Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV026==

~~Authors~~:

== Structural highlights ==

<table><tr><td colspan='2'>[[6os2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OS2 OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OS2 FirstGlance].

~~Description~~:

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='NonStdRes'><td class="sblockLbl">[[Non-Standard_Residue|NonStd Res:]]</td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6os2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6os2 OCA], [http://pdbe.org/6os2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6os2 RCSB], [http://www.ebi.ac.uk/pdbsum/6os2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6os2 ProSAT]</td></tr>

</table>

== Disease ==

[[http://www.uniprot.org/uniprot/AGTR1_HUMAN AGTR1_HUMAN]] NON RARE IN EUROPE: Essential hypertension;Renal tubular dysgenesis of genetic origin. The disease is caused by mutations affecting the gene represented in this entry.

== Function ==

[[http://www.uniprot.org/uniprot/AGTR1_HUMAN AGTR1_HUMAN]] Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Kleinhenz, A L.W]]

[[Category: Kruse, A C]]

[[Category: Lefkowitz, R J]]

[[Category: McMahon, C]]

[[Category: Skiba, M A]]

[[Category: Staus, D P]]

[[Category: Wingler, L M]]

[[Category: Gpcr]]

[[Category: Membrane protein]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6os2 is ON HOLD  until Paper Publication
+==Structure of synthetic nanobody-stabilized angiotensin II type 1 receptor bound to TRV026==
+<StructureSection load='6os2' size='340' side='right'caption='[[6os2]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
-Authors:
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6os2]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6OS2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6OS2 FirstGlance]. <br>
-Description:
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CLR:CHOLESTEROL'>CLR</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NH2:AMINO+GROUP'>NH2</scene>, <scene name='pdbligand=SAR:SARCOSINE'>SAR</scene></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6os2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6os2 OCA], [http://pdbe.org/6os2 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6os2 RCSB], [http://www.ebi.ac.uk/pdbsum/6os2 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6os2 ProSAT]</span></td></tr>
+</table>
+== Disease ==
+[[http://www.uniprot.org/uniprot/AGTR1_HUMAN AGTR1_HUMAN]] NON RARE IN EUROPE: Essential hypertension;Renal tubular dysgenesis of genetic origin. The disease is caused by mutations affecting the gene represented in this entry.
+== Function ==
+[[http://www.uniprot.org/uniprot/AGTR1_HUMAN AGTR1_HUMAN]] Receptor for angiotensin II. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system.
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Kleinhenz, A L.W]]
+[[Category: Kruse, A C]]
+[[Category: Lefkowitz, R J]]
+[[Category: McMahon, C]]
+[[Category: Skiba, M A]]
+[[Category: Staus, D P]]
+[[Category: Wingler, L M]]
+[[Category: Gpcr]]
+[[Category: Membrane protein]]