4hfx: Difference between revisions

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<StructureSection load='4hfx' size='340' side='right'caption='[[4hfx]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
<StructureSection load='4hfx' size='340' side='right'caption='[[4hfx]], [[Resolution|resolution]] 2.54&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4hfx]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HFX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4HFX FirstGlance]. <br>
<table><tr><td colspan='2'>[[4hfx]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4HFX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4HFX FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4hfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hfx OCA], [https://pdbe.org/4hfx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4hfx RCSB], [https://www.ebi.ac.uk/pdbsum/4hfx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4hfx ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4hfx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4hfx OCA], [http://pdbe.org/4hfx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4hfx RCSB], [http://www.ebi.ac.uk/pdbsum/4hfx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4hfx ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ELOA1_HUMAN ELOA1_HUMAN]] SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).  
[https://www.uniprot.org/uniprot/ELOA1_HUMAN ELOA1_HUMAN] SIII, also known as elongin, is a general transcription elongation factor that increases the RNA polymerase II transcription elongation past template-encoded arresting sites. Subunit A is transcriptionally active and its transcription activity is strongly enhanced by binding to the dimeric complex of the SIII regulatory subunits B and C (elongin BC complex).


==See Also==
==See Also==
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Acton, T B]]
[[Category: Acton TB]]
[[Category: Ciccosanti, C]]
[[Category: Ciccosanti C]]
[[Category: Everett, J K]]
[[Category: Everett JK]]
[[Category: Hunt, J F]]
[[Category: Hunt JF]]
[[Category: Montelione, G T]]
[[Category: Montelione GT]]
[[Category: Structural genomic]]
[[Category: Sahdev S]]
[[Category: Sahdev, S]]
[[Category: Seetharaman J]]
[[Category: Seetharaman, J]]
[[Category: Su M]]
[[Category: Su, M]]
[[Category: Tong L]]
[[Category: Tong, L]]
[[Category: Xiao R]]
[[Category: Xiao, R]]
[[Category: Nesg]]
[[Category: Psi-biology]]
[[Category: Transcription]]

Revision as of 08:14, 3 November 2022

Crystal structure of a transcription elongation factor B polypeptide 3 from Homo sapiens, Northeast Structural Genomics consortium target id HR4748B.

4hfx, resolution 2.54Å

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