6ppo: Difference between revisions
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==Rhinovirus C15 complexed with domain I of receptor CDHR3== | |||
<StructureSection load='6ppo' size='340' side='right'caption='[[6ppo]], [[Resolution|resolution]] 3.20Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6ppo]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/ ] and [http://en.wikipedia.org/wiki/Rhinovirus_c Rhinovirus c]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6PPO OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6PPO FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6ppo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6ppo OCA], [http://pdbe.org/6ppo PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6ppo RCSB], [http://www.ebi.ac.uk/pdbsum/6ppo PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6ppo ProSAT]</span></td></tr> | ||
[[Category: | </table> | ||
== Disease == | |||
[[http://www.uniprot.org/uniprot/CDHR3_HUMAN CDHR3_HUMAN]] Asthma susceptibility may be associated with variations affecting the gene represented in this entry in early childhood asthma with severe exacerbations occurring between 2 and 6 years of age.<ref>PMID:24241537</ref> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/CDHR3_HUMAN CDHR3_HUMAN]] Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. (Microbial infection) Acts as a receptor for rhinovirus C.<ref>PMID:25848009</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Rhinovirus c]] | |||
[[Category: Klose, T]] | [[Category: Klose, T]] | ||
[[Category: Palmenberg, A | [[Category: Palmenberg, A C]] | ||
[[Category: Sun, Y]] | [[Category: Sun, Y]] | ||
[[Category: Watters, K]] | |||
[[Category: Cadherin]] | |||
[[Category: Receptor]] | |||
[[Category: Virus-cell adhesion complex]] | |||