6vtk: Difference between revisions
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==Structure of an acid-sensing ion channel solubilized by styrene maleic acid and in a desensitized state at low pH== | |||
<StructureSection load='6vtk' size='340' side='right'caption='[[6vtk]], [[Resolution|resolution]] 2.82Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[6vtk]] is a 3 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6VTK OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6VTK FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6vtk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6vtk OCA], [http://pdbe.org/6vtk PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6vtk RCSB], [http://www.ebi.ac.uk/pdbsum/6vtk PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6vtk ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/ASIC1_CHICK ASIC1_CHICK]] Cation channel with high affinity for sodium, which is gated by extracellular protons and inhibited by the diuretic amiloride (By similarity).<ref>PMID:16002453</ref> | |||
== References == | |||
<references/> | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Gouaux, E]] | |||
[[Category: Yoder, N]] | |||
[[Category: Acid-sensing ion channel]] | |||
[[Category: Asic]] | |||
[[Category: Asic1a]] | |||
[[Category: Ion channel]] | |||
[[Category: Ligand-gated ion channel]] | |||
[[Category: Membrane protein]] | |||
[[Category: Proton-gated ion channel]] | |||
[[Category: Transport protein]] | |||
Revision as of 07:33, 11 March 2020
Structure of an acid-sensing ion channel solubilized by styrene maleic acid and in a desensitized state at low pH
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