2k36: Difference between revisions

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== Structural highlights ==

<table><tr><td colspan='2'>[[2k36]] is a 1 chain structure with sequence from [~~http~~://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K36 OCA]. For a <b>guided tour on the structure components</b> use [~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2K36 FirstGlance]. <br>

<table><tr><td colspan='2'>[[2k36]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K36 FirstGlance]. <br>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">K7R ([~~http~~://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>

</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">K7R ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[~~http~~://~~oca~~.~~weizmann.ac.il/oca-docs~~/fgij/fg.htm?mol=2k36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k36 OCA], [~~http~~://pdbe.org/2k36 PDBe], [~~http~~://www.rcsb.org/pdb/explore.do?structureId=2k36 RCSB], [~~http~~://www.ebi.ac.uk/pdbsum/2k36 PDBsum], [~~http~~://prosat.h-its.org/prosat/prosatexe?pdbcode=2k36 ProSAT]</span></td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k36 OCA], [https://pdbe.org/2k36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k36 RCSB], [https://www.ebi.ac.uk/pdbsum/2k36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k36 ProSAT]</span></td></tr>

</table>

== Function ==

[[~~http~~://www.uniprot.org/uniprot/K7_VACCW K7_VACCW]] Bcl-2-like protein which, through its interaction with the DEAD box RNA helicase DDX3X/DDX3, prevents TBK1/IKKepsilon-mediated IRF3 activation. Contributes to virulence by binding to the host TRAF6 and IRAK2 and preventing host NF-kappa-B activation.

[[https://www.uniprot.org/uniprot/K7_VACCW K7_VACCW]] Bcl-2-like protein which, through its interaction with the DEAD box RNA helicase DDX3X/DDX3, prevents TBK1/IKKepsilon-mediated IRF3 activation. Contributes to virulence by binding to the host TRAF6 and IRAK2 and preventing host NF-kappa-B activation.

== Publication Abstract from PubMed ==

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 <StructureSection load='2k36' size='340' side='right'caption='[[2k36]], [[NMR_Ensembles_of_Models | 15 NMR models]]' scene=''>
 == Structural highlights ==
-<table><tr><td colspan='2'>[[2k36]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K36 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2K36 FirstGlance]. <br>
+<table><tr><td colspan='2'>[[2k36]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Vaccinia_virus Vaccinia virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2K36 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2K36 FirstGlance]. <br>
-</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">K7R ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>
+</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">K7R ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10245 Vaccinia virus])</td></tr>
-<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2k36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k36 OCA], [http://pdbe.org/2k36 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2k36 RCSB], [http://www.ebi.ac.uk/pdbsum/2k36 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2k36 ProSAT]</span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2k36 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2k36 OCA], [https://pdbe.org/2k36 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2k36 RCSB], [https://www.ebi.ac.uk/pdbsum/2k36 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2k36 ProSAT]</span></td></tr>
 </table>
 == Function ==
-[[http://www.uniprot.org/uniprot/K7_VACCW K7_VACCW]] Bcl-2-like protein which, through its interaction with the DEAD box RNA helicase DDX3X/DDX3, prevents TBK1/IKKepsilon-mediated IRF3 activation. Contributes to virulence by binding to the host TRAF6 and IRAK2 and preventing host NF-kappa-B activation.
+[[https://www.uniprot.org/uniprot/K7_VACCW K7_VACCW]] Bcl-2-like protein which, through its interaction with the DEAD box RNA helicase DDX3X/DDX3, prevents TBK1/IKKepsilon-mediated IRF3 activation. Contributes to virulence by binding to the host TRAF6 and IRAK2 and preventing host NF-kappa-B activation.
 <div style="background-color:#fffaf0;">
 == Publication Abstract from PubMed ==