5r4k: Difference between revisions
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==PanDDA analysis group deposition -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF in complex with FMOPL000292a== | |||
<StructureSection load='5r4k' size='340' side='right'caption='[[5r4k]], [[Resolution|resolution]] 1.17Å' scene=''> | |||
== Structural highlights == | |||
<table><tr><td colspan='2'>[[5r4k]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5R4K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5R4K FirstGlance]. <br> | |||
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=K0V:methyl+1-(tert-butylcarbamoyl)piperidine-4-carboxylate'>K0V</scene>, <scene name='pdbligand=TRS:2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL'>TRS</scene></td></tr> | |||
[[Category: | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5r4k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5r4k OCA], [http://pdbe.org/5r4k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5r4k RCSB], [http://www.ebi.ac.uk/pdbsum/5r4k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5r4k ProSAT]</span></td></tr> | ||
</table> | |||
== Function == | |||
[[http://www.uniprot.org/uniprot/BPTF_HUMAN BPTF_HUMAN]] Histone-binding component of NURF (nucleosome-remodeling factor), a complex which catalyzes ATP-dependent nucleosome sliding and facilitates transcription of chromatin. Specifically recognizes H3 tails trimethylated on 'Lys-4' (H3K4me3), which mark transcription start sites of virtually all active genes. May also regulate transcription through direct binding to DNA or transcription factors. | |||
__TOC__ | |||
</StructureSection> | |||
[[Category: Large Structures]] | |||
[[Category: Aimon, A]] | [[Category: Aimon, A]] | ||
[[Category: Arrowsmith, C H]] | |||
[[Category: Bountra, C]] | |||
[[Category: Bradley, A R]] | |||
[[Category: Brandao-Neto, J]] | |||
[[Category: Brennan, P E]] | |||
[[Category: Collins, P]] | [[Category: Collins, P]] | ||
[[Category: | [[Category: Delft, F von]] | ||
[[Category: | [[Category: Dias, A]] | ||
[[Category: Douangamath, A]] | |||
[[Category: Edwards, A]] | |||
[[Category: Fairhead, M]] | [[Category: Fairhead, M]] | ||
[[Category: | [[Category: Krojer, T]] | ||
[[Category: MacLean, E]] | |||
[[Category: Renjie, Z]] | [[Category: Renjie, Z]] | ||
[[Category: Sethi, R]] | |||
[[Category: Talon, R]] | |||
[[Category: Wright, N]] | [[Category: Wright, N]] | ||
[[Category: | [[Category: Bptf]] | ||
[[Category: | [[Category: Bromodomain]] | ||
[[Category: | [[Category: Bromodomain and phd finger-containing transcription factor]] | ||
[[Category: | [[Category: Fac1]] | ||
[[Category: | [[Category: Falz]] | ||
[[Category: | [[Category: Fetal alz-50 clone 1 protein]] | ||
[[Category: | [[Category: Pandda]] | ||
[[Category: | [[Category: Sgc - diamond i04-1 fragment screening]] | ||
[[Category: | [[Category: Transcription]] | ||
[[Category: | [[Category: Xchemexplorer]] | ||
Revision as of 09:04, 1 April 2020
PanDDA analysis group deposition -- CRYSTAL STRUCTURE OF THE BROMODOMAIN OF HUMAN NUCLEOSOME-REMODELING FACTOR SUBUNIT BPTF in complex with FMOPL000292a
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Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Large Structures
- Aimon, A
- Arrowsmith, C H
- Bountra, C
- Bradley, A R
- Brandao-Neto, J
- Brennan, P E
- Collins, P
- Delft, F von
- Dias, A
- Douangamath, A
- Edwards, A
- Fairhead, M
- Krojer, T
- MacLean, E
- Renjie, Z
- Sethi, R
- Talon, R
- Wright, N
- Bptf
- Bromodomain
- Bromodomain and phd finger-containing transcription factor
- Fac1
- Falz
- Fetal alz-50 clone 1 protein
- Pandda
- Sgc - diamond i04-1 fragment screening
- Transcription
- Xchemexplorer
