6y6f: Difference between revisions

Line 1:

~~'''Unreleased structure'''~~

~~The entry~~ 6y6f is ~~ON HOLD~~

==Crystal structure of STK17B (DRAK2) in complex with PKIS43==

~~Authors~~: ~~Chaikuad~~, A., ~~Arrowsmith~~, C.H., ~~Edwards~~, A.M., ~~Bountra~~, C., ~~Drewry~~, D.~~, Knapp, S~~.~~, Structural Genomics Consortium (SGC)~~

== Structural highlights ==

<table><tr><td colspan='2'>[[6y6f]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y6F OCA]. For a guided tour on the structure components use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Y6F FirstGlance].

~~Description~~: ~~Crystal structure of STK17B~~ (~~DRAK2~~) ~~in complex with PKIS43~~

</td></tr><tr id='ligand'><td class="sblockLbl">[[Ligand|Ligands:]]</td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OD2:2-[6-(4-methylsulfanylphenyl)thieno[3,2-d]pyrimidin-4-yl]sulfanylethanoic+acid'>OD2</scene></td></tr>

[[Category: ~~Unreleased~~ Structures]]

<tr id='activity'><td class="sblockLbl">Activity:</td><td class="sblockDat">[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </td></tr>

<tr id='resources'><td class="sblockLbl">Resources:</td><td class="sblockDat">[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6y6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y6f OCA], [http://pdbe.org/6y6f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6y6f RCSB], [http://www.ebi.ac.uk/pdbsum/6y6f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6y6f ProSAT]</td></tr>

</table>

== Function ==

[[http://www.uniprot.org/uniprot/ST17B_HUMAN ST17B_HUMAN]] Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.<ref>PMID:9786912</ref>

== References ==

__TOC__

</StructureSection>

[[Category: Large Structures]]

[[Category: Non-specific serine/threonine protein kinase]]

[[Category: Arrowsmith, C H]]

[[Category: Bountra, C]]

[[Category: Chaikuad, A]]

[[Category: ~~Arrowsmith~~, ~~C.H~~]]

[[Category: Drewry, D]]

[[Category: Edwards, A M]]

[[Category: Knapp, S]]

[[Category: ~~Drewry, D~~]]

[[Category: Structural genomic]]

[[Category: ~~Edwards, A.M~~]]

[[Category: Chemical probe]]

[[Category: ~~Structural Genomics Consortium (~~Sgc)]]

[[Category: Drak2]]

[[Category: ~~Bountra, C~~]]

[[Category: Kinase]]

[[Category: Kinase inhibitor]]

[[Category: Pki]]

[[Category: Sgc]]

[[Category: Transferase]]

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@@ Line 1: / Line 1: @@
-'''Unreleased structure'''
-The entry 6y6f is ON HOLD
+==Crystal structure of STK17B (DRAK2) in complex with PKIS43==
+<StructureSection load='6y6f' size='340' side='right'caption='[[6y6f]], [[Resolution|resolution]] 1.98&Aring;' scene=''>
-Authors: Chaikuad, A., Arrowsmith, C.H., Edwards, A.M., Bountra, C., Drewry, D., Knapp, S., Structural Genomics Consortium (SGC)
+== Structural highlights ==
+<table><tr><td colspan='2'>[[6y6f]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=6Y6F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6Y6F FirstGlance]. <br>
-Description: Crystal structure of STK17B (DRAK2) in complex with PKIS43
+</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=OD2:2-[6-(4-methylsulfanylphenyl)thieno[3,2-d]pyrimidin-4-yl]sulfanylethanoic+acid'>OD2</scene></td></tr>
-[[Category: Unreleased Structures]]
+<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Non-specific_serine/threonine_protein_kinase Non-specific serine/threonine protein kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.1 2.7.11.1] </span></td></tr>
+<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=6y6f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=6y6f OCA], [http://pdbe.org/6y6f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=6y6f RCSB], [http://www.ebi.ac.uk/pdbsum/6y6f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=6y6f ProSAT]</span></td></tr>
+</table>
+== Function ==
+[[http://www.uniprot.org/uniprot/ST17B_HUMAN ST17B_HUMAN]] Phosphorylates myosin light chains (By similarity). Acts as a positive regulator of apoptosis.<ref>PMID:9786912</ref>
+== References ==
+<references/>
+__TOC__
+</StructureSection>
+[[Category: Large Structures]]
+[[Category: Non-specific serine/threonine protein kinase]]
+[[Category: Arrowsmith, C H]]
+[[Category: Bountra, C]]
 [[Category: Chaikuad, A]]
-[[Category: Arrowsmith, C.H]]
+[[Category: Drewry, D]]
+[[Category: Edwards, A M]]
 [[Category: Knapp, S]]
-[[Category: Drewry, D]]
+[[Category: Structural genomic]]
-[[Category: Edwards, A.M]]
+[[Category: Chemical probe]]
-[[Category: Structural Genomics Consortium (Sgc)]]
+[[Category: Drak2]]
-[[Category: Bountra, C]]
+[[Category: Kinase]]
+[[Category: Kinase inhibitor]]
+[[Category: Pki]]
+[[Category: Sgc]]
+[[Category: Transferase]]