1h9f: Difference between revisions

<table><tr><td colspan='2'>[[1h9f]] is a 1 chain structure. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1H9F OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1H9F FirstGlance]. <br>

</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1h9e|1h9e]]</td></tr>

<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1h9f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1h9f OCA], [http://pdbe.org/1h9f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1h9f RCSB], [http://www.ebi.ac.uk/pdbsum/1h9f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1h9f ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/LAP2A_HUMAN LAP2A_HUMAN]] Defects in TMPO are the cause of cardiomyopathy dilated type 1T (CMD1T) [MIM:[http://omim.org/entry/613740 613740]]. A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.<ref>PMID:16247757</ref>   

[[http://www.uniprot.org/uniprot/LAP2A_HUMAN LAP2A_HUMAN]] May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly. Plays an important role, together with LMNA, in the nuclear anchorage of RB1.  TP and TP5 may play a role in T-cell development and function. TP5 is an immunomodulating pentapeptide.