5c3t: Difference between revisions

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<StructureSection load='5c3t' size='340' side='right'caption='[[5c3t]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='5c3t' size='340' side='right'caption='[[5c3t]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5c3t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C3T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C3T FirstGlance]. <br>
<table><tr><td colspan='2'>[[5c3t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C3T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C3T FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zqk|4zqk]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c3t OCA], [https://pdbe.org/5c3t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c3t RCSB], [https://www.ebi.ac.uk/pdbsum/5c3t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c3t ProSAT]</span></td></tr>
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">CD274, B7H1, PDCD1L1, PDCD1LG1, PDL1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c3t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c3t OCA], [http://pdbe.org/5c3t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c3t RCSB], [http://www.ebi.ac.uk/pdbsum/5c3t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5c3t ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/PD1L1_HUMAN PD1L1_HUMAN]] Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.<ref>PMID:10581077</ref> <ref>PMID:11015443</ref>
[https://www.uniprot.org/uniprot/PD1L1_HUMAN PD1L1_HUMAN] Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.<ref>PMID:10581077</ref> <ref>PMID:11015443</ref>  
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Dubin, G]]
[[Category: Dubin G]]
[[Category: Holak, T A]]
[[Category: Holak TA]]
[[Category: Zak, K M]]
[[Category: Zak KM]]
[[Category: Immune system]]
[[Category: Immunology]]
[[Category: Ligand]]
[[Category: Pd1/pdl1 axis]]
Retrieved from "https://proteopedia.org/5c3t"