5c4w: Difference between revisions

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<StructureSection load='5c4w' size='340' side='right'caption='[[5c4w]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
<StructureSection load='5c4w' size='340' side='right'caption='[[5c4w]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[5c4w]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Coxsackievirus_a16 Coxsackievirus a16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C4W OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5C4W FirstGlance]. <br>
<table><tr><td colspan='2'>[[5c4w]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Coxsackievirus_A16 Coxsackievirus A16]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5C4W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5C4W FirstGlance]. <br>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SPH:SPHINGOSINE'>SPH</scene></td></tr>
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=SPH:SPHINGOSINE'>SPH</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5c4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c4w OCA], [http://pdbe.org/5c4w PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5c4w RCSB], [http://www.ebi.ac.uk/pdbsum/5c4w PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5c4w ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5c4w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5c4w OCA], [https://pdbe.org/5c4w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5c4w RCSB], [https://www.ebi.ac.uk/pdbsum/5c4w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5c4w ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/I3W9E1_9ENTO I3W9E1_9ENTO]] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611]  Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266]  RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]  
[https://www.uniprot.org/uniprot/I3W9E1_9ENTO I3W9E1_9ENTO] Protein 2C associates with and induces structural rearrangements of intracellular membranes. It displays RNA-binding, nucleotide binding and NTPase activities (By similarity).[SAAS:SAAS000199_004_016611]  Protein 3C is a cysteine protease that generates mature viral proteins from the precursor polyprotein. In addition to its proteolytic activity, it binds to viral RNA, and thus influences viral genome replication. RNA and substrate bind co-operatively to the protease (By similarity).[SAAS:SAAS000199_004_042266]  RNA-directed RNA polymerase 3D-POL replicates genomic and antigenomic RNA by recognizing replications specific signals (By similarity).[SAAS:SAAS000199_004_010047]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5c4w" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5c4w" style="background-color:#fffaf0;"></div>
==See Also==
*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Coxsackievirus a16]]
[[Category: Coxsackievirus A16]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Fry, E E]]
[[Category: Fry EE]]
[[Category: Gao, Q]]
[[Category: Gao Q]]
[[Category: Hu, Z]]
[[Category: Hu Z]]
[[Category: Li, X]]
[[Category: Li X]]
[[Category: Rao, Z]]
[[Category: Rao Z]]
[[Category: Ren, J]]
[[Category: Ren J]]
[[Category: Shen, X]]
[[Category: Shen X]]
[[Category: Stuart, D I]]
[[Category: Stuart DI]]
[[Category: Wang, J]]
[[Category: Wang J]]
[[Category: Wang, X]]
[[Category: Wang X]]
[[Category: Yang, P]]
[[Category: Yang P]]
[[Category: Zhu, L]]
[[Category: Zhu L]]
[[Category: Hand-foot-and-mouth disease]]
[[Category: Icosahedral virus]]
[[Category: Immunogenicity]]
[[Category: Picornavirus]]
[[Category: Virus]]
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