Sandbox 20001

Coronavirus Disease 2019 (COVID-19)

spinqualitylabelsall models Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D COVID-19 This illustration, created at the Centers for Disease Control and Prevention (CDC), reveals ultrastructural morphology exhibited by coronaviruses. Note the spikes that adorn the outer surface of the virus, which impart the look of a corona surrounding the virion, when viewed electron microscopically. A novel coronavirus, named Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2), was identified as the cause of an outbreak of respiratory illness first detected in Wuhan, China in 2019. The illness caused by this virus has been named coronavirus disease 2019 (COVID-19). Photo credit: Alissa Eckert, MS; Dan Higgins, MAMS Key Sites The Centers for Disease Control and Prevention (CDC) devoted to COVID-19 Recent published papers A recent study by Gautret et al. (2020) showed, despite its small sample size (20 patients treated), that hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients and its effect is reinforced by azithromycin. Scientists are endeavoring to find antivirals specific to the virus. Several drugs such as chloroquine, arbidol, remdesivir, and favipiravir are currently undergoing clinical studies to test their efficacy and safety in the treatment of COVID-19 in China; some promising results have been achieved thus far and are summarizes agents with potential efficacy against SARS-CoV-2. 2017 Nobel laureate Richard Henderson explains the History of cryo-EM in this video, 5 min.