Sandbox 20003: Difference between revisions
From Proteopedia
Jump to navigationJump to search
No edit summary |
No edit summary |
||
| Line 23: | Line 23: | ||
== Potential treatments and ways to minimize exposure to COVID-19 == | == Potential treatments and ways to minimize exposure to COVID-19 == | ||
* A USA, French UK study '''identified 69 drugs to test against the coronavirus'''<ref> Gordon, et al. A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing: bioRxiv (online) 2020 [http://doi.org/10.1101/2020.03.22.002386 http://doi.org/10.1101/2020.03.22.002386]</ref>. As reported in the [http://www.nytimes.com/2020/03/22/science/coronavirus-drugs-chloroquine.html?action=click&module=Top%20Stories&pgtype=Homepage New York Times] (23-Mar-2020) "The researchers sought drugs that also latch onto the human proteins that the coronavirus seems to need to enter and replicate in human cells." | * A USA, French UK study '''identified 69 drugs to test against the coronavirus'''<ref> Gordon, et al. A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing: bioRxiv (online) 2020 [http://doi.org/10.1101/2020.03.22.002386 http://doi.org/10.1101/2020.03.22.002386]</ref>. As reported in the [http://www.nytimes.com/2020/03/22/science/coronavirus-drugs-chloroquine.html?action=click&module=Top%20Stories&pgtype=Homepage New York Times] (23-Mar-2020) "The researchers sought drugs that also latch onto the human proteins that the coronavirus seems to need to enter and replicate in human cells." | ||
* Fighting Coronavirus with Soap from PDB-101. | * Fighting Coronavirus with Soap from PDB-101. | ||
<html5media width=" | <html5media width="250">https://www.youtube.com/watch?v=s2EVlqql_f8</html5media> | ||
* A French study<ref> Gautret, et al. Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open- label non-randomized clinical trial: Intl J Antimcrob Agents (in press) 2020 [http://dx.doi.org/10.1016/j.ijantimicag.2020.105949 http://dx.doi.org/10.1016/j.ijantimicag.2020.105949]</ref> showed, despite its small sample size (20 patients treated), that '''hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients''' and its effect is reinforced by azithromycin. | * A French study<ref> Gautret, et al. Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open- label non-randomized clinical trial: Intl J Antimcrob Agents (in press) 2020 [http://dx.doi.org/10.1016/j.ijantimicag.2020.105949 http://dx.doi.org/10.1016/j.ijantimicag.2020.105949]</ref> showed, despite its small sample size (20 patients treated), that '''hydroxychloroquine treatment is significantly associated with viral load reduction/disappearance in COVID-19 patients''' and its effect is reinforced by azithromycin. | ||
| Line 30: | Line 31: | ||
== Movies helping to explain COVID-19 == | == Movies helping to explain COVID-19 == | ||
* Coronavirus animation: How COVID-19 Impacts your Body and ways to avoid infection (Mar 20 2020), by [http://highimpact.com High Impact]. | * Coronavirus animation: How COVID-19 Impacts your Body and ways to avoid infection (Mar 20 2020), by [http://highimpact.com High Impact]. | ||
<html5media width=" | <html5media height="181" width="322">https://www.youtube.com/watch?v=78jLBNSqc3g</html5media> | ||
* Background of the Coronavirus-COVID-19 and details of its 3D structure, by [http://www.biolution.net biolution GmBH]. | * Background of the Coronavirus-COVID-19 and details of its 3D structure, by [http://www.biolution.net biolution GmBH]. | ||
<html5media height="181 | <html5media height="181">https://www.youtube.com/watch?v=I0TmBsHaGmI</html5media> | ||
* A [http://player.vimeo.com/video/395937110?html5=1&title=1&byline=0&portrait=0&autoplay=0 movie of the 3D model] of the surface of COVID-19, by [http://www.drugtargetreview.com/news/57287/3d-visualisation-of-covid-19-surface-released-for-researchers Fusion Animation]. | * A [http://player.vimeo.com/video/395937110?html5=1&title=1&byline=0&portrait=0&autoplay=0 movie of the 3D model] of the surface of COVID-19, by [http://www.drugtargetreview.com/news/57287/3d-visualisation-of-covid-19-surface-released-for-researchers Fusion Animation]. | ||
