2qzf: Difference between revisions

<table><tr><td colspan='2'>[[2qzf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2QZF OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2QZF FirstGlance]. <br>

</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2qzf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2qzf OCA], [http://pdbe.org/2qzf PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2qzf RCSB], [http://www.ebi.ac.uk/pdbsum/2qzf PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2qzf ProSAT]</span></td></tr>

[[http://www.uniprot.org/uniprot/DAF_HUMAN DAF_HUMAN]] This protein recognizes C4b and C3b fragments that condense with cell-surface hydroxyl or amino groups when nascent C4b and C3b are locally generated during C4 and c3 activation. Interaction of daf with cell-associated C4b and C3b polypeptides interferes with their ability to catalyze the conversion of C2 and factor B to enzymatically active C2a and Bb and thereby prevents the formation of C4b2a and C3bBb, the amplification convertases of the complement cascade.<ref>PMID:7525274</ref>