4ckg: Difference between revisions

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<SX load='4ckg' size='340' side='right' viewer='molstar' caption='[[4ckg]], [[Resolution|resolution]] 12.00&Aring;' scene=''>
<SX load='4ckg' size='340' side='right' viewer='molstar' caption='[[4ckg]], [[Resolution|resolution]] 12.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ckg]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CKG OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=4CKG FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ckg]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4CKG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4CKG FirstGlance]. <br>
</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4ckh|4ckh]]</td></tr>
</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ckg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ckg OCA], [https://pdbe.org/4ckg PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ckg RCSB], [https://www.ebi.ac.uk/pdbsum/4ckg PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ckg ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=4ckg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ckg OCA], [http://pdbe.org/4ckg PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4ckg RCSB], [http://www.ebi.ac.uk/pdbsum/4ckg PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4ckg ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
[[http://www.uniprot.org/uniprot/ACAP1_HUMAN ACAP1_HUMAN]] GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.<ref>PMID:11062263</ref> <ref>PMID:16256741</ref> <ref>PMID:17398097</ref> <ref>PMID:17664335</ref> <ref>PMID:22645133</ref>
[[https://www.uniprot.org/uniprot/ACAP1_HUMAN ACAP1_HUMAN]] GTPase-activating protein (GAP) for ADP ribosylation factor 6 (ARF6) required for clathrin-dependent export of proteins from recycling endosomes to trans-Golgi network and cell surface. Required for regulated export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration.<ref>PMID:11062263</ref> <ref>PMID:16256741</ref> <ref>PMID:17398097</ref> <ref>PMID:17664335</ref> <ref>PMID:22645133</ref>  
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== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
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[[Category: Human]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
[[Category: Deng, Y C]]
[[Category: Deng YC]]
[[Category: Fan, J]]
[[Category: Fan J]]
[[Category: Gao, B Q]]
[[Category: Gao BQ]]
[[Category: Hsu, V]]
[[Category: Hsu V]]
[[Category: Li, J]]
[[Category: Li J]]
[[Category: Ma, J]]
[[Category: Ma J]]
[[Category: Pang, X Y]]
[[Category: Pang XY]]
[[Category: Sun, F]]
[[Category: Sun F]]
[[Category: Zhang, K]]
[[Category: Zhang K]]
[[Category: Zhang, Y]]
[[Category: Zhang Y]]
[[Category: Zhou, Q J]]
[[Category: Zhou QJ]]
[[Category: Membrane remodeling]]
[[Category: Signaling protein]]